Transition-metal-catalyzed C–H bond activation for the formation of C–C bonds in complex molecules

JH Docherty, TM Lister, G Mcarthur, MT Findlay… - Chemical …, 2023 - ACS Publications
Site-predictable and chemoselective C–H bond functionalization reactions offer synthetically
powerful strategies for the step-economic diversification of both feedstock and fine …

Designing sites in heterogeneous catalysis: are we reaching selectivities competitive with those of homogeneous catalysts?

F Zaera - Chemical Reviews, 2022 - ACS Publications
A critical review of different prominent nanotechnologies adapted to catalysis is provided,
with focus on how they contribute to the improvement of selectivity in heterogeneous …

Recent advances in transition-metal-catalyzed carbene insertion to C–H bonds

Y He, Z Huang, K Wu, J Ma, YG Zhou… - Chemical Society Reviews, 2022 - pubs.rsc.org
C–H functionalization has been emerging as a powerful method to establish carbon–carbon
and carbon–heteroatom bonds. Many efforts have been devoted to transition-metal …

Key Green Chemistry research areas from a pharmaceutical manufacturers' perspective revisited

MC Bryan, PJ Dunn, D Entwistle, F Gallou… - Green …, 2018 - pubs.rsc.org
In 2007 the members of the ACS Green Chemistry Institute® Pharmaceutical Roundtable
assembled a list of key green chemistry research areas to both identify transformations that …

The medicinal chemist's toolbox for late stage functionalization of drug-like molecules

T Cernak, KD Dykstra, S Tyagarajan… - Chemical Society …, 2016 - pubs.rsc.org
The advent of modern C–H functionalization chemistries has enabled medicinal chemists to
consider a synthetic strategy, late stage functionalization (LSF), which utilizes the C–H …

Recent advances in metal-catalysed asymmetric sigmatropic rearrangements

Y Liu, X Liu, X Feng - Chemical Science, 2022 - pubs.rsc.org
Asymmetric sigmatropic rearrangement is a powerful organic transformation via substrate-
reorganization to efficiently increase molecular complexity from readily accessible starting …

Recent perspectives on rearrangement reactions of ylides via carbene transfer reactions

S Jana, Y Guo, RM Koenigs - Chemistry–A European Journal, 2021 - Wiley Online Library
Among the available methods to increase the molecular complexity, sigmatropic
rearrangements occupy a distinct position in organic synthesis. Despite being known for …

Pushing the boundaries of C–H bond functionalization chemistry using flow technology

S Govaerts, A Nyuchev, T Noel - Journal of Flow Chemistry, 2020 - Springer
C–H functionalization chemistry is one of the most vibrant research areas within synthetic
organic chemistry. While most researchers focus on the development of small-scale batch …

Transition metal-catalyzed [2, 3]-sigmatropic rearrangements of ylides: An update of the most recent advances

Z Sheng, Z Zhang, C Chu, Y Zhang, J Wang - Tetrahedron, 2017 - Elsevier
Abstract [2, 3]-sigmatropic rearrangements of ylides are useful methods for synthesizing
functional molecules, especially for these containing heteroatoms. This short report focuses …

Catalytic stereoselective [2, 3]-rearrangement reactions

TH West, SSM Spoehrle, K Kasten, JE Taylor… - ACS …, 2015 - ACS Publications
[2, 3]-Sigmatropic rearrangement processes of allylic ylides or their equivalents can be
applied to a variety of different substrates and generate products of wide …