Cellular therapy aims to replace damaged resident cells by restoring cellular and molecular
environments suitable for tissue repair and regeneration. Among several candidates …

Human mesenchymal stem/stromal cell (hMSC)-based cell therapies are promising for
treating a variety of diseases. The unique immunomodulatory properties of hMSCs have …

Life expectancy and age-related diseases burden increased significantly over the past few
decades. Age-related conditions are commonly discussed in a very limited paradigm of …

Natural ageing of organisms and corresponding age-related diseases result mainly from
stem cell ageing and “inflammaging”. Mesenchymal stem cells (MSCs) exhibit very high …

Pulsed electromagnetic field (PEMF) is emerging as innovative treatment for regulation of
inflammation, which could have significant effects on tissue regeneration. PEMF modulates …

Background aims Human mesenchymal stromal cells (MSCs) are being used in clinical
trials, but the best protocol to prepare the cells for administration to patients remains unclear …

The horse is an attractive model for many human age-related degenerative diseases of the
musculoskeletal system because it is a large animal species that both ages and exercises …

Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) develops rapidly and
has high mortality. ALI/ARDS is mainly manifested as acute or progressive hypoxic …

Background Considering promising results in animal models and patients, therapeutic use
of MSCs for immune disease is likely to undergo continued evaluation. Low-lever laser (LLL) …

Tobacco smoking is the main environmental risk factor for chronic obstructive pulmonary
disease (COPD), but not all smokers develop the disease. A population of lung-resident …