Neural circuits driving larval locomotion in Drosophila

MQ Clark, AA Zarin, A Carreira-Rosario, CQ Doe - Neural development, 2018 - Springer
More than 30 years of studies into Drosophila melanogaster neurogenesis have revealed
fundamental insights into our understanding of axon guidance mechanisms, neural …

Central pattern generating networks in insect locomotion

C Mantziaris, T Bockemühl… - Developmental …, 2020 - Wiley Online Library
Central pattern generators (CPGs) are neural circuits that based on their connectivity can
generate rhythmic and patterned output in the absence of rhythmic external inputs. This …

A circuit mechanism for the propagation of waves of muscle contraction in Drosophila

A Fushiki, MF Zwart, H Kohsaka, RD Fetter, A Cardona… - Elife, 2016 - elifesciences.org
Animals move by adaptively coordinating the sequential activation of muscles. The circuit
mechanisms underlying coordinated locomotion are poorly understood. Here, we report on …

Divergent connectivity of homologous command-like neurons mediates segment-specific touch responses in Drosophila

S Takagi, BT Cocanougher, S Niki, D Miyamoto… - Neuron, 2017 - cell.com
Animals adaptively respond to a tactile stimulus by choosing an ethologically relevant
behavior depending on the location of the stimuli. Here, we investigate how somatosensory …

Reactive oxygen species regulate activity-dependent neuronal plasticity in Drosophila

MCW Oswald, PS Brooks, MF Zwart, A Mukherjee… - elife, 2018 - elifesciences.org
Reactive oxygen species (ROS) have been extensively studied as damaging agents
associated with ageing and neurodegenerative conditions. Their role in the nervous system …

Regulation of forward and backward locomotion through intersegmental feedback circuits in Drosophila larvae

H Kohsaka, MF Zwart, A Fushiki, RD Fetter… - Nature …, 2019 - nature.com
Animal locomotion requires spatiotemporally coordinated contraction of muscles throughout
the body. Here, we investigate how contractions of antagonistic groups of muscles are …

Anatomy and Neural Pathways Modulating Distinct Locomotor Behaviors in Drosophila Larva

SBM Gowda, S Salim, F Mohammad - Biology, 2021 - mdpi.com
Simple Summary Simple movements require the involvement of many neurons before a
group of muscles receives the signal to contract and relax. The sensory system adds another …

Neural circuits underlying fly larval locomotion

H Kohsaka, P A. Guertin, A Nose - Current pharmaceutical …, 2017 - benthamdirect.com
Locomotion is a complex motor behavior that may be expressed in different ways using a
variety of strategies depending upon species and pathological or environmental conditions …

Modelling the mechanics of exploration in larval Drosophila

J Loveless, K Lagogiannis, B Webb - PLoS computational biology, 2019 - journals.plos.org
The Drosophila larva executes a stereotypical exploratory routine that appears to consist of
stochastic alternation between straight peristaltic crawling and reorientation events through …

Recording neural activity in unrestrained animals with three-dimensional tracking two-photon microscopy

D Karagyozov, MM Skanata, A Lesar, M Gershow - Cell reports, 2018 - cell.com
Optical recordings of neural activity in behaving animals can reveal the neural correlates of
decision making, but brain motion, which often accompanies behavior, compromises these …