Behaviours such as eating, copulating, defending oneself or taking addictive drugs begin
with a motivation to initiate the behaviour. Both this motivational drive and the behaviours …

Physicians, policymakers, and researchers are increasingly focused on finding ways to
decrease opioid use and overdose in the United States both of which have sharply …

Importance Chronic opioid use imposes a substantial burden in terms of morbidity and
economic costs. Whether opioid-naive patients undergoing surgery are at increased risk for …

Importance Prolonged opioid use after surgery may be associated with opioid dependency
and increased health care use. However, published studies have reported varying estimates …

Objectives To identify trends in concurrent use of a benzodiazepine and an opioid and to
identify the impact of these trends on admissions to hospital and emergency room visits for …

ABSTRACT BACKGROUND Chronic opioid therapy for chronic pain treatment has
increased. Hospital physicians, including hospitalists and medical/surgical resident …

Background: While persistent opioid use after surgery has been the subject of a large
number of studies, it is unknown how much variability in the definition of persistent use …

Importance Opioids are commonly used for pain control during and after invasive
procedures. However, opioid-related adverse drug events (ORADEs) are common and have …

Abstract National Pain Strategy population research objectives include: estimating chronic
pain prevalence, studying pain treatment with electronic health care data, and developing …

Study Design. Prospective cohort. Objective. To assess whether preoperative opioid use is
associated with increased perioperative opioid demand and postoperative opioid …