Polymeric nitric oxide delivery nanoplatforms for treating cancer, cardiovascular diseases, and infection

G Jin, Z Gao, Y Liu, J Zhao, H Ou… - Advanced Healthcare …, 2021 - Wiley Online Library
The shortened Abstract is as follows: Therapeutic gas nitric oxide (NO) has demonstrated
the unique advances in biomedical applications due to its prominent role in regulating …

Engineering macromolecular nanocarriers for local delivery of gaseous signaling molecules

J Hu, Y Fang, X Huang, R Qiao, JF Quinn… - Advanced Drug Delivery …, 2021 - Elsevier
In addition to being notorious air pollutants, nitric oxide (NO), carbon monoxide (CO), and
hydrogen sulfide (H 2 S) have also been known as endogenous gaseous signaling …

Magnetic Responsive Release of Nitric Oxide from an MOF-Derived Fe3O4@PLGA Microsphere for the Treatment of Bacteria-Infected Cutaneous Wound

CW Chung, BW Liao, SW Huang… - … Applied Materials & …, 2022 - ACS Publications
Nitric oxide (NO) is an essential endogenous signaling molecule regulating multifaceted
physiological functions in the (cardio) vascular, neuronal, and immune systems. Due to the …

Nitric oxide-releasing poly(lactic-co-glycolic acid)-polyethylenimine nanoparticles for prolonged nitric oxide release, antibacterial efficacy, and in vivo wound healing …

H Nurhasni, J Cao, M Choi, I Kim, BL Lee… - International journal …, 2015 - Taylor & Francis
Nitric oxide (NO)-releasing nanoparticles (NPs) have emerged as a wound healing
enhancer and a novel antibacterial agent that can circumvent antibiotic resistance. However …

Mussel-inspired catalytic selenocystamine-dopamine coatings for long-term generation of therapeutic gas on cardiovascular stents

Z Yang, Y Yang, L Zhang, K Xiong, X Li, F Zhang… - Biomaterials, 2018 - Elsevier
The development of a nitric oxide (NO)-generating surface with long-term, stable and
controllable NO release improves the therapeutic efficacy of cardiovascular stents. In this …

PEI/NONOates-doped PLGA nanoparticles for eradicating methicillin-resistant Staphylococcus aureus biofilm in diabetic wounds via binding to the biofilm matrix

N Hasan, J Cao, J Lee, M Naeem, SP Hlaing… - Materials Science and …, 2019 - Elsevier
Wounds infected with methicillin-resistant Staphylococcus aureus (MRSA) biofilm represent
a high risk in patients with diabetes. Nitric oxide (NO) has shown promise in dispersing …

A dual pH-sensitive liposomal system with charge-reversal and NO generation for overcoming multidrug resistance in cancer

M Chen, F Song, Y Liu, J Tian, C Liu, R Li, Q Zhang - Nanoscale, 2019 - pubs.rsc.org
In cancer therapy, chemotherapeutic drugs frequently encounter multidrug resistance (MDR)
induced by the overexpression of drug transporters such as P-glycoprotein (P-gp). Herein, in …

Bacteria-adhesive nitric oxide-releasing graphene oxide nanoparticles for MRPA-infected wound healing therapy

J Cao, SP Hlaing, J Lee, J Kim, EH Lee… - … Applied Materials & …, 2022 - ACS Publications
A bacteria-infected wound can lead to being life-threatening and raises a great economic
burden on the patient. Here, we developed polyethylenimine 1.8 k (PEI1. 8k) surface …

Nitric oxide releasing coronary stent: a new approach using layer‐by‐layer coating and liposomal encapsulation

MA Elnaggar, SH Seo, S Gobaa, KS Lim, IH Bae… - Small, 2016 - Wiley Online Library
The sustained or controlled release of nitric oxide (NO) can be the most promising approach
for the suppression or prevention of restenosis and thrombosis caused by stent implantation …

Controlled nitric oxide release using poly (lactic-co-glycolic acid) nanoparticles for anti-inflammatory effects

Y Oh, H Jeong, S Lim, J Hong - Biomacromolecules, 2020 - ACS Publications
Nitric oxide (NO) plays a key role in several physiological functions such as inflammatory
responses and immune regulation. However, despite its beneficial functions, the short half …