Bacterial chromosomes are folded to compact DNA and facilitate cellular processes.
Studying model bacteria has revealed aspects of chromosome folding that are applicable to …

Every organism across the tree of life compacts and organizes its genome with architectural
chromatin proteins. While eukaryotes and archaea express histone proteins, the …

Cyclic di-GMP (c-di-GMP) is a second messenger that transduces extracellular stimuli into
cellular responses and regulates various biological processes in bacteria. H-NS is a global …

Nucleoid-associated proteins (NAPs) play a central role in chromosome organization and
environment-responsive transcription regulation. The Bacillus subtilis-encoded NAP Rok …

In eukaryotes, histone paralogues form obligate heterodimers such as H3/H4 and H2A/H2B
that assemble into octameric nucleosome particles. Archaeal histones are dimeric and …

Colonization factors (CFs) are major virulence factors of enterotoxigenic Escherichia coli
(ETEC). This pathogen is among the most common causes of bacterial diarrhea in children …

Nucleoid‐associated proteins (NAPs) are architectural proteins of the bacterial chromosome
and transcription factors that dynamically organise the chromosome and regulate gene …

H-NS, the histone-like nucleoid-structuring protein in bacteria, regulates the stability of the
bacterial genome by inhibiting the transcription of horizontally transferred genes, such as the …

Environmentally regulated gene expression is critical for bacterial survival under stress
conditions, including extremes in temperature, osmolarity and nutrient availability. Here, we …

Escherichia coli K-12 possesses two versions of Trk/Ktr/HKT-type potassium ion (K+)
transporters, TrkG and TrkH. The current paradigm is that TrkG and TrkH have largely …