Solid lipid nanoparticles and nanostructured lipid carriers: A review of the methods of manufacture and routes of administration

J Akbari, M Saeedi, F Ahmadi… - Pharmaceutical …, 2022 - Taylor & Francis
The bioavailability of drugs is dependent on several factors such as solubility and the
administration route. A drug with poor aqueous solubility, therefore, poses challenges with …

Innovative topical niosomal gel formulation containing diclofenac sodium (niofenac)

J Akbari, M Saeedi, K Morteza-Semnani… - Journal of Drug …, 2022 - Taylor & Francis
The purpose of this research was to enhance the transdermal delivery of diclofenac sodium
niosomal formulations. To characterise the obtained niosomes, SEM, XRPD, DSC and ATR …

An eco-friendly and hopeful promise platform for delivering hydrophilic wound healing agents in topical administration for wound disorder: diltiazem-loaded niosomes

J Akbari, M Saeedi, K Morteza-Semnani… - Journal of …, 2023 - Springer
Purposes Calcium channel blockers, such as diltiazem (DLZ), are important drugs for wound
repair treatment. This current study used an ultrasonic method to increase the cutaneous …

Eco-friendly preparation, characterization, evaluation of anti-melanogenesis/antioxidant effect and in vitro/in vivo safety profile of kojic acid loaded niosome as skin …

M Saeedi, K Morteza-Semnani, J Akbari… - Journal of …, 2023 - Taylor & Francis
In the current study, an ultrasonic approach (as green method) was utilized to prepared kojic
acid niosome (kojisome) which aimed to increase the dermal delivery and improving anti …

Green formulation, characterization, antifungal and biological safety evaluation of terbinafine HCl niosomes and niosomal gels manufactured by eco-friendly green …

K Morteza-Semnani, M Saeedi, J Akbari… - Journal of …, 2022 - Taylor & Francis
Terbinafine (TER) is a promising candidate medication for the topical treatment of fungal
infections. However, its solubility in water and skin permeability are limited. To overcome …

Brain targeting of venlafaxine HCl as a hydrophilic agent prepared through green lipid nanotechnology

M Saeedi, K Morteza-Semnani, J Akbari… - Journal of Drug Delivery …, 2021 - Elsevier
This study aimed to improve venlafaxine HCl brain delivery using solid lipid nanoparticles
(SLNs) made by an ultrasonication method. The impact of the ratio of two surfactants …

Hyaluronic Acid‐Coated Chitosan/Gelatin Nanoparticles as a New Strategy for Topical Delivery of Metformin in Melanoma

P Ebrahimnejad, A Rezaeiroshan… - BioMed Research …, 2023 - Wiley Online Library
Metformin is a multipotential compound for treating diabetes II and controlling hormonal
acne and skin cancer. This study was designed to enhance metformin skin penetration in …

Green preparation, characterization, wound healing assessment, and histopathological evaluation of Vitamin A encapsulated in niosome and solid lipid nanoparticle

SM Rahimnia, M Saeedi… - Pharmaceutical …, 2023 - ps.tbzmed.ac.ir
Background: The purpose of the current work was to manufacture vitamin A (Vit A) niosome
and solid lipid nanoparticle (SLN) using an ultrasonic approach and to evaluate its effect on …

Green formulation of spironolactone loaded chitosan-coated nano lipid carrier for treatment of acne vulgaris: A randomized double-blind clinical trial

M Saeedi, K Morteza-Semnani, J Akbari… - Advanced …, 2023 - pmc.ncbi.nlm.nih.gov
Purpose: Spironolactone (SPN), which is classified as an anti-androgen, has demonstrated
efficacy in treating acne. This study aimed to utilize ultrasonication to create a chitosan …

Development of kojic acid loaded collagen-chitosan nanoparticle as skin lightener product: in vitro and in vivo assessment

M Saeedi, K Morteza-Semnani, J Akbari… - Journal of …, 2024 - Taylor & Francis
In the present study, an ionic gelation and ultrasonic approach was performed to produce
kojic acid (KA) loaded chitosan (CS)/collagen (CN) nanoparticle (NP)(CSCN-NP) which …