Recent evidence shows that transplantation of neural stem/precursor cells may protect the
central nervous system from inflammatory damage through a'bystander'mechanism that is …

No effective therapy is currently available to promote recovery following ischemic stroke.
Stem cells have been proposed as a potential source of new cells to replace those lost due …

Autologous transplantation of patient-specific induced pluripotent stem cell (iPSC)-derived
neurons is a potential clinical approach for treatment of neurological disease. Preclinical …

The retina is subject to degenerative conditions, leading to blindness. Although retinal
regeneration is robust in lower vertebrates, regeneration does not occur in the adult …

The main motor symptoms of Parkinson's disease are due to the loss of dopaminergic (DA)
neurons in the ventral midbrain (VM). For the future treatment of Parkinson's disease with …

Stem cells from human exfoliated deciduous teeth (SHED) have been identified as a novel
population of postnatal stem cells capable of differentiating into neural cells, odontogenic …

Substitutive cell therapy using fetal striatal grafts has demonstrated preliminary clinical
success in patients with Huntington's disease, but the logistics required for accessing fetal …

We show that human embryonic stem cell-derived dopaminergic neurons survived
transplantation to the neurotoxin 6-hydroxydopamine-lesioned rat striatum and, in …

For the safe clinical application of embryonic stem cells (ESCs) for neurological diseases, it
is critical to evaluate the tumorigenicity and function of human ESC (hESC)‐derived neural …

Clinical application of stem cell derivatives requires clinical-grade cells and sufficient
preclinical proof of safety and efficacy, preferably in primates. We previously successfully …