Background Reducing high blood cholesterol, a risk factor for cardiovascular disease (CVD)
events in people with and without a past history of coronary heart disease (CHD) is an …

Multiple sclerosis (MS) is a chronic progressive disabling disease of the central nervous
system (CNS) characterized by demyelination and neuronal injury. Dyslipidemia is observed …

Background Secondary progressive multiple sclerosis, for which no satisfactory treatment
presently exists, accounts for most of the disability in patients with multiple sclerosis …

Regional differences in neurons, astrocytes, oligodendrocytes, and microglia exist in the
brain during health, and regional differences in the transcriptome may occur for each cell …

Statins, a class of cholesterol-lowering medications that inhibit 3-hydroxy-3-methyl-glutaryl-
coenzyme A reductase, are commonly administered to treat atherosclerotic cardiovascular …

Abstract Purpose of Review In this review, we provide a comprehensive update on current
scientific advances and emerging therapeutic approaches in the field of multiple sclerosis …

Isoflavones are secondary metabolites that represent the most abundant category of plant
polyphenols. Dietary soy, kudzu, and red clover contain primarily genistein, daidzein …

Objectives: This trial examined the efficacy of a stress management program in reducing
neuroimaging markers of multiple sclerosis (MS) disease activity. Methods: A total of 121 …

Persistent neuroinflammation is now recognized as a chief pathological component of
practically all neurodegenerative diseases. Neuroinflammation in the central nervous …

In recent years it has become clear that the neuronal compartment already plays an
important role early in the pathology of multiple sclerosis (MS). Neuronal injury in the course …