[HTML][HTML] Obesity, male infertility, and the sperm epigenome

JR Craig, TG Jenkins, DT Carrell, JM Hotaling - Fertility and sterility, 2017 - Elsevier
Obesity is a growing epidemic and a common problem among reproductive-age men that
can both cause and exacerbate male-factor infertility by means of endocrine abnormalities …

Male infertility

A Agarwal, S Baskaran, N Parekh, CL Cho, R Henkel… - The Lancet, 2021 - thelancet.com
It is estimated that infertility affects 8–12% of couples globally, with a male factor being a
primary or contributing cause in approximately 50% of couples. Causes of male subfertility …

Causes and risk factors for male infertility: a scoping review of published studies

FE Okonofua, LFC Ntoimo, A Omonkhua… - … Journal of General …, 2022 - Taylor & Francis
Background Despite the evidence of declining sperm counts worldwide and the increasing
prevalence of male infertility, there has been limited documentation of the potential causes …

Male adiposity, sperm parameters and reproductive hormones: An updated systematic review and collaborative meta‐analysis

A Salas‐Huetos, L Maghsoumi‐Norouzabad… - Obesity …, 2021 - Wiley Online Library
The present updated systematic review and meta‐analysis aims to summarize the evidence
from published studies with low risk for any important bias (based on methodological quality …

Association of diabetes and obesity with sperm parameters and testosterone levels: a meta-analysis

O Zhong, L Ji, J Wang, X Lei, H Huang - Diabetology & Metabolic …, 2021 - Springer
Background The present study performed two distinct meta-analyses with common
outcomes (sperm parameters); one was performed in obese individuals (and non-obese …

Investigation and management of subfertility

L Thurston, A Abbara, WS Dhillo - Journal of clinical pathology, 2019 - jcp.bmj.com
Subfertility affects one in seven couples and is defined as the inability to conceive after 1
year of regular unprotected intercourse. This article describes the initial clinical evaluation …

Does an increase in adipose tissue 'weight'affect male fertility? A systematic review and meta‐analysis based on semen analysis performed using the WHO 2010 …

D Santi, F Lotti, C Sparano, G Rastrelli, AM Isidori… - …, 2024 - Wiley Online Library
Introduction Obesity negatively impact on the metabolism of sex hormones, leading to
reduced testosterone serum levels. However, how the obesity could negatively impact on …

Association between obesity and sperm quality

GA Ramaraju, S Teppala, K Prathigudupu… - Andrologia, 2018 - Wiley Online Library
There is awareness of likelihood of abnormal spermatozoa in obese men; however, results
from previous studies are inconclusive. Advances in computer‐aided sperm analysis …

Association between body mass index and sperm quality and sperm DNA integrity. A large population study

JBA Oliveira, CG Petersen, AL Mauri, LD Vagnini… - Andrologia, 2018 - Wiley Online Library
This study aimed to analyse whether the functional quality of spermatozoa is associated with
body mass index (BMI). Semen samples were obtained from 1824 men undergoing fertility …

Metabolic syndrome and male fertility

AD Martins, A Majzoub… - The world journal of men's …, 2019 - synapse.koreamed.org
Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on
human health overall. Its prevalence has been rapidly increasing worldwide and has …