Muscle development and lipid accumulation in muscle critically affect meat quality of
livestock. However, the genetic factors underlying myofiber-type specification and …

After the knock-out (KO) of α1, 3 galactosyltransfease (Gal-T), the Hanganutziu-Deicher
antigen became a major antigen of the" non-Gal antigen" that is implicated in subsequent …

Recent progress in genetic manipulation of pigs designated for xenotransplantation ha6s
shown considerable promise on xenograft survival in primates. However, genetic …

Many transgenic domestic animals have been developed to produce therapeutic proteins in
the mammary gland, and this approach is one of the most important methods for agricultural …

The article discusses about the status of xenotransplantation in South Korea. Topics of
discussion includes initiation of Xenotransplantation Research Center (XRC) at the Seoul …

Porcine heart xenotransplantation is a potential treatment for patients with end-stage heart
failure. To understand molecular mechanisms of graft rejection after heart transplantation …

In this study, we examined whether Hanganutziu-Deicher (HD) antigens are important as an
immunogenic non-α1, 3-galactose (Gal) epitope in pigs with a disrupted α1, 3 …

Xenotransplantation of pig organs into primates leads to hyperacute rejection (HAR).
Functional ablation of the pig α 1, 3-galactosyltransferase (GalT) gene, which abrogates …

Background Solid organ xenotransplantation is a potential solution to current organ
shortages in allotransplantation. We performed four heart transplantations from alpha1, 3 …

We examined whether deficiency of the GGTA1 gene in pigs altered the expression of
several glycosyltransferase genes. Real‐time RT‐PCR and glycosyltransferase activity …