Mycobacterium tuberculosis cell-wall and antimicrobial peptides: a mission impossible?
YM Jacobo-Delgado, A Rodríguez-Carlos… - Frontiers in …, 2023 - frontiersin.org
Mycobacterium tuberculosis (Mtb) is one of the most important infectious agents worldwide
and causes more than 1.5 million deaths annually. To make matters worse, the drug …
and causes more than 1.5 million deaths annually. To make matters worse, the drug …
Nanotherapeutics for pulmonary drug delivery: An emerging approach to overcome respiratory diseases
Pulmonary diseases pose an immense threat to global health. Several nanotherapeutics-
based approaches aimed to tackle pulmonary ailments in recent years. The current …
based approaches aimed to tackle pulmonary ailments in recent years. The current …
Clofazimine nanoclusters show high efficacy in experimental TB with amelioration in paradoxical lung inflammation
The rise of tuberculosis (TB) superbugs has impeded efforts to control this infectious ailment,
and new treatment options are few. Paradoxical Inflammation (PI) is another major problem …
and new treatment options are few. Paradoxical Inflammation (PI) is another major problem …
Trans-nasal brain delivery of anti-TB drugs by methyl-β-cyclodextrin microparticles show efficient mycobacterial clearance from central nervous system
Central nervous system tuberculosis (CNS-TB) is the most severe extra-pulmonary
manifestation of tuberculosis (TB), facing significant challenges due to the limited …
manifestation of tuberculosis (TB), facing significant challenges due to the limited …
Breaking the Cycle: Matrix Metalloproteinase Inhibitors as an Alternative Approach in Managing Tuberculosis Pathogenesis and Progression
Mycobacterium tuberculosis (Mtb) has long posed a significant challenge to global public
health, resulting in approximately 1.6 million deaths annually. Pulmonary tuberculosis (TB) …
health, resulting in approximately 1.6 million deaths annually. Pulmonary tuberculosis (TB) …
Antibiotic Resistance to Mycobacterium tuberculosis and Potential Use of Natural and Biological Products as Alternative Anti-Mycobacterial Agents
R Arrigoni, A Ballini, S Topi, L Bottalico, E Jirillo… - Antibiotics, 2022 - mdpi.com
Background: Tuberculosis (TB) is an infectious disease caused by the bacillus
Mycobacterium tuberculosis (Mtb). TB treatment is based on the administration of three …
Mycobacterium tuberculosis (Mtb). TB treatment is based on the administration of three …
Engineered vildagliptin-loaded polymeric nanoparticles via microfluidic and spray drying for enhanced antidiabetic activity
Background Vildagliptin (VLG), an antidiabetic agent, presents a potential solution to this
widespread affliction. It exhibits notable attributes, such as a high solubility and a shorter …
widespread affliction. It exhibits notable attributes, such as a high solubility and a shorter …
Targeted delivery of the metastasis-specific tumour homing TMTP1 peptide to non-small-cell lung cancer (NSCLC) using inhalable hybrid nano-assemblies
Lung cancer is one of the most fatal malignancies, with the highest death rate (∼ 19%), and
the NSCLC type accounts for∼ 85% of lung cancers. In the search for new treatments …
the NSCLC type accounts for∼ 85% of lung cancers. In the search for new treatments …
Inhalable chitosan-coated nano-assemblies potentiate niclosamide for targeted abrogation of non-small-cell lung cancer through dual modulation of autophagy and …
Lung carcinoma, particularly non-small-cell lung cancer (NSCLC), accounts for a significant
portion of cancer-related deaths, with a fatality rate of approximately 19%. Niclosamide …
portion of cancer-related deaths, with a fatality rate of approximately 19%. Niclosamide …
Host-Directed Therapy with Inhalable Lovastatin Microspheres for Matrix Metalloproteinase Inhibition in Tuberculosis
Tuberculosis (TB) triggers a robust immune response, which leads to significant destruction
of the lung tissue at the site of infection, aiding in the transmission of Mycobacterium …
of the lung tissue at the site of infection, aiding in the transmission of Mycobacterium …