MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines
In patients presenting with a clinically isolated syndrome, MRI can support and substitute
clinical information in the diagnosis of multiple sclerosis by showing disease dissemination …
clinical information in the diagnosis of multiple sclerosis by showing disease dissemination …
Outcome measures in clinical trials for multiple sclerosis
CEP van Munster, BMJ Uitdehaag - CNS drugs, 2017 - Springer
Due to the heterogeneous nature of the disease, it is a challenge to capture disease activity
of multiple sclerosis (MS) in a reliable and valid way. Therefore, it can be difficult to assess …
of multiple sclerosis (MS) in a reliable and valid way. Therefore, it can be difficult to assess …
Association of slowly expanding lesions on MRI with disability in people with secondary progressive multiple sclerosis
A Calvi, FP Carrasco, C Tur, DT Chard, J Stutters… - Neurology, 2022 - AAN Enterprises
Background and Objective To explore the relationship between slowly expanding lesions
(SELs) on MRI and disability in secondary progressive multiple sclerosis (SPMS). Methods …
(SELs) on MRI and disability in secondary progressive multiple sclerosis (SPMS). Methods …
In vivo imaging of chronic active lesions in multiple sclerosis
New clinical activity in multiple sclerosis (MS) is often accompanied by acute inflammation
which subsides. However, there is growing evidence that a substantial proportion of lesions …
which subsides. However, there is growing evidence that a substantial proportion of lesions …
Volumetric analysis from a harmonized multisite brain MRI study of a single subject with multiple sclerosis
BACKGROUND AND PURPOSE: MR imaging can be used to measure structural changes in
the brains of individuals with multiple sclerosis and is essential for diagnosis, longitudinal …
the brains of individuals with multiple sclerosis and is essential for diagnosis, longitudinal …
Diagnosis of progressive multiple sclerosis from the imaging perspective: a review
M Filippi, P Preziosa, F Barkhof, DT Chard… - JAMA …, 2021 - jamanetwork.com
Importance Although magnetic resonance imaging (MRI) is useful for monitoring disease
dissemination in space and over time and excluding multiple sclerosis (MS) mimics, there …
dissemination in space and over time and excluding multiple sclerosis (MS) mimics, there …
[HTML][HTML] Cortical lesions, central vein sign, and paramagnetic rim lesions in multiple sclerosis: Emerging machine learning techniques and future avenues
The current diagnostic criteria for multiple sclerosis (MS) lack specificity, and this may lead to
misdiagnosis, which remains an issue in present-day clinical practice. In addition …
misdiagnosis, which remains an issue in present-day clinical practice. In addition …
[HTML][HTML] Slowly expanding lesions relate to persisting black-holes and clinical outcomes in relapse-onset multiple sclerosis
Abstract Background Slowly expanding lesions (SELs) are MRI markers of chronic active
lesions in multiple sclerosis (MS). T1-hypointense black holes, and reductions in …
lesions in multiple sclerosis (MS). T1-hypointense black holes, and reductions in …
The role of T1-weighted derived measures of neurodegeneration for assessing disability progression in multiple sclerosis
Introduction Multiple sclerosis (MS) is characterised by the accumulation of permanent
neurological disability secondary to irreversible tissue loss (neurodegeneration) in the brain …
neurological disability secondary to irreversible tissue loss (neurodegeneration) in the brain …
Outcome measures in relapsing‐remitting multiple sclerosis: capturing disability and disease progression in clinical trials
AM Lavery, LH Verhey… - Multiple sclerosis …, 2014 - Wiley Online Library
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease that
manifests as acute relapses and progressive disability. As a primary endpoint for clinical …
manifests as acute relapses and progressive disability. As a primary endpoint for clinical …