Contemporary approaches to site-selective protein modification

EA Hoyt, PMSD Cal, BL Oliveira… - Nature Reviews …, 2019 - nature.com
Proteins constitute the majority of nature's worker biomolecules. Designed for specific
functions, complex tertiary structures make proteins ideal candidates for analysing natural …

Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Chemical conjugation to less targeted proteinogenic amino acids

NL Kjærsgaard, TB Nielsen, KV Gothelf - ChemBioChem, 2022 - Wiley Online Library
Protein bioconjugates are in high demand for applications in biomedicine, diagnostics,
chemical biology and bionanotechnology. Proteins are large and sensitive molecules …

Carboxymethylated Dextran-Modified N-Heterocyclic Carbene Self-Assembled Monolayers on Gold for Use in Surface Plasmon Resonance Biosensing

Z Li, MR Narouz, K Munro, B Hao… - … applied materials & …, 2017 - ACS Publications
Surface chemistry is a key enabler for various biosensing applications. Biosensors based on
surface plasmon resonance routinely employ thiol-based chemistry for the linker layer …

Improvement of the Photophysical Performance of Platinum‐Cyclometalated Complexes in Halogen‐Bonded Adducts

V Sivchik, RK Sarker, ZY Liu, KY Chung… - … A European Journal, 2018 - Wiley Online Library
Three groups of luminescent platinum complexes [Pt (C^ N)(L)(Y)][C^ N= benzothienyl‐
pyridine (1), bezofuryl‐pyridine (2), phenyl‐pyridine (3); L/Y= DMSO/Cl (a), PPh3/Cl (b) …

Water-soluble cyclometalated platinum (II) and iridium (III) complexes: Synthesis, tuning of the photophysical properties, and in vitro and in vivo phosphorescence …

AI Solomatina, SH Su, MM Lukina, VV Dudenkova… - RSC …, 2018 - pubs.rsc.org
This paper presents synthesis and photophysical investigation of cyclometalated water-
soluble Pt (II) and Ir (III) complexes containing auxiliary sulfonated diphosphine (bis …

Reactions of Cyclometalated Platinum(II) [Pt(NC)(PR3)Cl] Complexes with Imidazole and Imidazole-Containing Biomolecules: Fine-Tuning of Reactivity and …

AI Solomatina, PS Chelushkin, TO Abakumova… - Inorganic …, 2018 - ACS Publications
This work describes interaction of a family of [Pt (N∧ C)(PR3) Cl] complexes with imidazole
(Im), possible application of this chemistry for regioselective labeling of proteins through …

A cyclometalated trinuclear Ir (iii)/Pt (ii) complex as a luminescent probe for histidine-rich proteins

A Sarkar, R Kumar, B Das, PS Ray, P Gupta - Dalton Transactions, 2020 - pubs.rsc.org
Organometallic complexes have important application in the field of protein staining, with
potential for use in proteomic analysis. The rational synthesis of a trinuclear luminescent …

Phosphorescence lifetime imaging (PLIM): State of the art and perspectives

PS Chelushkin, SP Tunik - Progress in Photon Science: Recent Advances, 2019 - Springer
This chapter reviews the status and perspectives of phosphorescence lifetime imaging
(PLIM), an advanced imaging strategy that relies on phosphorescence lifetime measuring as …

Classical vs. non-classical cyclometalated Pt (II) complexes

L Maidich, MI Pilo, JP Rourke, GJ Clarkson, P Canu… - Molecules, 2022 - mdpi.com
Rollover cyclometalated complexes constitute a family of derivatives which differ from
classical cyclometalated species in certain aspects. Various potential application fields have …