Osteosarcoma, the most common malignant tumor of the bone, seriously influences people's
lives and increases their economic burden. Conventional chemotherapy drugs achieve …

A variety of targeted nanoparticles were developed for the diagnosis and therapy of
orthotopic and metastatic bone tumors during the past decade. This critical review will focus …

Therapeutic efficacy of a systemic drug delivery largely depends on the targeting design of
the delivery system, which tackles with circulatory traffic and prevents the nonspecific …

Administration of nanomaterials based medicinal and drug carrier systems into systemic
circulation brings about interaction of blood components eg albumin and globulin proteins …

In the present study, a biomimetic nanoconstruct (BNc) with a multimodal imaging system is
engineered using tumor homing natural killer cell membrane (NKM), near‐infrared (NIR) …

Biodegradable and biocompatible polymeric nanoparticles (NPs) stand out as a key tool for
improving drug bioavailability, reducing the inherent toxicity, and targeting the intended site …

The use of nanoparticles as biomaterials with applications in the biomedical field is growing
every day. These nanomaterials can be used as contrast imaging agents, combination …

Stem cells are well-known for their great capacity for tissue regeneration. This provides a
promising source for cell-based therapies in treating various bone degenerative disorders …

Extracellular adenosine has been shown to play a key role in maintaining bone health and
could potentially be used to treat bone loss. However, systemic administration of exogenous …

Osteoporosis (OP) is characterized by a loss in bone mass and mineral density. The
stimulation of the canonical Wnt/β-catenin pathway has been reported to promote bone …