Co-carrier-based solid dispersion of celecoxib improves dissolution rate and oral bioavailability in rats

P Tran, TN Nguyen, JS Park - Journal of Drug Delivery Science and …, 2023 - Elsevier
This study aimed to prepare a co-carrier-based solid dispersion (SD) of celecoxib (CXB) to
improve its dissolution and oral bioavailability. The CXB-loaded SD formulation was …

Brazilian red propolis extract free and encapsulated into polymeric nanoparticles against ovarian cancer: formulation, characterisation and biological assays in 2D and …

IA Justino, A Marincek, IRS Ferreira… - Journal of Pharmacy …, 2023 - academic.oup.com
Cancer incidence worldwide is alarming and among the cancers that affect women ovarian
cancer is the most fatal. Many side effects are associated with conventional therapies and …

Fabrication and evaluation of cefpodoxime proxetil niosomes

B Fouziya, AA Hindustan, SC Dontha… - Asian Journal of …, 2022 - indianjournals.com
The authors aimed to create and characterise Cefpodoxime Proxetil (CDP) niosomes with
site-specific delivery in order to minimise disruptions in gastric disintegration and absorption …

[PDF][PDF] Solid dispersion tablets in improving oral bioavailability of poorly soluble drugs

P Sarkar, S Das, SB Majee - Int J Curr Pharm Sci, 2022 - academia.edu
Recent advances in the field of conversion of solid dispersions of poorly water-soluble drugs
in a wide range of hydrophilic or water-soluble carriers into solid dispersion tablets have …

A comprehensive report on solid dispersions by factorial design

HA Ahad, H Chinthaginjala, S Rahamtulla, BP Pallavi… - 2021 - indianjournals.com
The drugs of present use are lipophilic. Hence there is a need to surge the solubility of these
drugs. To encounter this necessity one of the approaches is the formulation of drugs in form …

[HTML][HTML] Curcumin-loaded soluplus® based ternary solid dispersions with enhanced solubility, dissolution and antibacterial, antioxidant, anti-inflammatory activities

M Ishtiaq, H Manzoor, IU Khan, S Asghar, M Irfan… - Heliyon, 2024 - cell.com
Amorphous solid dispersion (ASD) has emerged to be an outstanding strategy among
multiple options available for improving solubility and consequently biological activity …

[HTML][HTML] Complex dispersions of poloxamers and mesoporous carriers with ibrutinib

IA Dain, SA Zolotov, NB Demina, AS Zolotova… - OpenNano, 2022 - Elsevier
Ibrutinib is an anticancer drug, a Bruton's tyrosine kinase inhibitor with poor solubility in
aqueous media. This study reports on the study of the effectiveness of mesoporous carriers …

[PDF][PDF] Optimizing Verapamil Hydrochloride In-situ Delivery: A Strategic Formulation Approach using Box-Behnken Design for Enhanced Performance and …

RK Choudhary, S Beeraka, BK Sarkar… - … Journal of Drug …, 2024 - researchgate.net
This study focuses on formulating and assessing an in-situ gastro-retentive gel for precise
delivery of verapamil hydrochloride to the stomach, aiming to extend its residence time and …

Development, characterization in vitro and in silico of coenzyme Q10 loaded myristic acid with different liquid lipids nanostructured lipid carriers

NLD Aryani, S Siswandono, W Soeratri… - … of Pharmacy & …, 2021 - repository.ubaya.ac.id
Context: Nanostructured lipid carriers can enhance skin penetration of active substances.
Coenzyme Q10 is a lipophilic antioxidant, that has poor skin penetration. This limitation is …

[HTML][HTML] Recent and relevant methodology in the advancement of solid dispersion

S Talla, K Wadher, M Umekar… - Journal of Drug Delivery …, 2021 - jddtonline.info
Most of the promising drugs in development channels are poorly water-soluble drugs which
limit formulation approaches, clinical application because of their low dissolution and …