Visualization and quantification of the adverse effects of distorted blood flow are important
emerging fields in cardiology. Abnormal blood flow patterns can be seen in various …

Patient-specific cardiovascular simulations can provide clinicians with predictive tools, fill
current gaps in clinical imaging capabilities, and contribute to the fundamental …

Simulations of blood flow in both healthy and diseased vascular models can be used to
compute a range of hemodynamic parameters including velocities, time varying wall shear …

Purpose To evaluate viscous energy loss and the association with three‐dimensional (3D)
vortex ring formation in left ventricular (LV) blood flow during diastolic filling. Theory and …

Objective Elevated energy loss in the total cavopulmonary connection (TCPC) is
hypothesised to have a detrimental effect on clinical outcomes in single-ventricle physiology …

Fluid mechanics plays a key role in the development, progression, and treatment of
cardiovascular disease. Advances in imaging methods and patient-specific modeling now …

Wall shear stress (WSS) plays a governing role in vascular remodeling and a pathogenic
role in vessel wall diseases. However, little is known of the normal WSS patterns in the aorta …

Children born with single ventricle heart defects typically undergo a staged surgical
procedure culminating in a total cavopulmonary connection (TCPC) or Fontan surgery. The …

Coupling shape optimization to three-dimensional unsteady cardiovascular simulations
poses several key challenges, including high computational cost, a need to handle …

Objective: To apply flow-sensitive magnetic resonance imaging for the evaluation of whole-
heart flow characteristics in healthy volunteers and patients with Fontan circulation …