The escalating human population all over the globe has posed serious threats such asa
limited supply of resources (non-renewable), increasing environmental pollution, global …

The sustainable use of resources is essential in all production areas, including
pharmaceuticals. However, the aspect of sustainability needs to be taken into consideration …

The preparation of optically pure fine chemicals is among the most important and
challenging tasks met by organic chemists. Recently, significant efforts have been focused …

One current approach in the treatment of cancer is the inhibition of cyclin dependent kinase
(CDK) enzymes with small molecules. CDK are a class of enzymes, which catalyze the …

A series of α-aminophosphonates (3a-3m) bearing the sulfisoxazole moiety was synthesized
through one-pot Kabachnik-Fields reaction of sulfisoxazole, diethyl phosphite (DEP) and …

A four-component and one-pot synthesis involving N, S-acetalation of aldehydes with
cysteine followed by the reaction with second aldehydes for decarboxylative [3​+​ 2] …

1, 3-Dipolar cycloaddition of nonstabilized azomethine ylides derived from α-C–H
functionalization of tetrahydroisoquinoline for regio-and diastereoselective synthesis of …

A metal‐free sequential one‐pot three‐component protocol is described for the synthesis of
C3‐functionalized imidazo [1, 2‐a] pyridines. A successive construction of imidazo [1, 2‐a] …

Heterocyclic chemistry is an essential frontier in science and a source of novel biologically
active compounds. The development of innovative synthetic methodologies that allows …

An efficient procedure was proposed for the synthesis of 3 (5)-substituted 1, 2, 4-triazol-5 (3)-
amines via a one-pot reaction of thiourea, dimethyl sulfate and various hydrazides. 1, 2, 4 …