The role of adipose tissue in cardiovascular health and disease

EK Oikonomou, C Antoniades - Nature Reviews Cardiology, 2019 - nature.com
Accumulating knowledge on the biology and function of the adipose tissue has led to a
major shift in our understanding of its role in health and disease. The adipose tissue is now …

Vitamin A signaling and homeostasis in obesity, diabetes, and metabolic disorders

WS Blaner - Pharmacology & therapeutics, 2019 - Elsevier
Much evidence has accumulated in the literature over the last fifteen years that indicates
vitamin A has a role in metabolic disease prevention and causation. This literature proposes …

Impact of retinoic acid on immune cells and inflammatory diseases

LM Oliveira, FME Teixeira… - Mediators of inflammation, 2018 - Wiley Online Library
Vitamin A metabolite retinoic acid (RA) plays important roles in cell growth, differentiation,
organogenesis, and reproduction and a key role in mucosal immune responses. RA …

[HTML][HTML] Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes

A Kaisanlahti, T Glumoff - Journal of physiology and biochemistry, 2019 - Springer
Mammalian adipose tissue is traditionally categorized into white and brown relating to their
function and morphology: while white serves as an energy storage, brown adipose tissue …

Retinoic acid and its derivatives in skin

Ł Szymański, R Skopek, M Palusińska, T Schenk… - Cells, 2020 - mdpi.com
The retinoids are a group of compounds including vitamin A and its active metabolite all-
trans-retinoic acid (ATRA). Retinoids regulate a variety of physiological functions in multiple …

The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity

I AlZaim, LPMH de Rooij, BN Sheikh… - Nature Reviews …, 2023 - nature.com
Adipose tissue is an endocrine organ and a crucial regulator of energy storage and systemic
metabolic homeostasis. Additionally, adipose tissue is a pivotal regulator of cardiovascular …

An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications

Z Ghesmati, M Rashid, S Fayezi, F Gieseler… - Reviews in Endocrine …, 2024 - Springer
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and
beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT …

β-carotene in obesity research: technical considerations and current status of the field

J Coronel, I Pinos, J Amengual - Nutrients, 2019 - mdpi.com
Over the past decades, obesity has become a rising health problem as the accessibility to
high calorie, low nutritional value food has increased. Research shows that some bioactive …

Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation

AW Fischer, MY Jaeckstein, K Gottschling, M Heine… - Cell metabolism, 2021 - cell.com
In response to cold exposure, thermogenic adipocytes internalize large amounts of fatty
acids after lipoprotein lipase-mediated hydrolysis of triglyceride-rich lipoproteins (TRL) in the …

Carotenoids and carotenoid conversion products in adipose tissue biology and obesity: Pre-clinical and human studies

ML Bonet, J Ribot, S Galmés, F Serra… - Biochimica et Biophysica …, 2020 - Elsevier
Antiobesity activities of carotenoids and carotenoid conversion products (CCPs) have been
demonstrated in pre-clinical studies, and mechanisms behind have begun to be unveiled …