P Yang, Y Zhu, Q Zheng, S Meng, Y Wu… - European journal of …, 2022 - Elsevier
The Wnt/β-catenin signaling pathway is involved in many cellular physiological processes, including embryonic development, cell proliferation and differentiation, tissue homeostasis …
H Zhang, C Liu, D Zhu, Q Zhang… - Journal of Medicinal …, 2022 - ACS Publications
Dysregulation of the Wnt/β-catenin signaling pathway is strongly associated with various aspects of cancer, including tumor initiation, proliferation, and metastasis as well as …
X Zhao, Y Ma, J Luo, K Xu, P Tian, C Lu, J Song - Heliyon, 2024 - cell.com
The WNT/β-catenin signaling pathway plays crucial roles in tumorigenesis and relapse, metastasis, drug resistance, and tumor stemness maintenance. In most tumors, the WNT/β …
W Zhu, C Liu, K Xi, A Li, L Shen, Y Li… - Journal of Medicinal …, 2024 - ACS Publications
Aberrant activation of the Wnt/β-catenin signaling is associated with tumor development, and blocking β-catenin/BCL9 is a novel strategy for oncogenic Wnt/β-catenin signaling. Herein …
P Sang, Y Shi, L Wei, J Cai - RSC Chemical Biology, 2022 - pubs.rsc.org
Sulfono-γ-AApeptides are a subset of possible sequence-specific foldamers that might be considered for the design of biomimetic drug molecular structures. Although they have been …
Aberrant activation of Wnt/β-catenin signaling is strongly associated with many diseases including cancer invasion and metastasis. Small-molecule targeting of the central signaling …
Z Wang, M Zhang, HM Thompson… - ACS Medicinal Chemistry …, 2022 - ACS Publications
A series of 1-(3-(2-amino-2-oxoethoxy) phenyl) piperidine-3-carboxamide derivatives was reported as new small-molecule β-catenin/B-cell lymphoma 9 (BCL9) protein–protein …
The Wnt/β‐catenin signaling pathway is associated with activating genes that support cell proliferation, differentiation, and survival. Excessive activation of Wnt/β‐catenin signaling …
N Bao, L Cheng, Y Wang, Z Peng, Z Wang… - Frontiers in …, 2022 - frontiersin.org
Methamphetamine (MA) is the most common and highly addictive substance abuse drug. Runt-related transcription factor 3 (RUNX3) and Zinc finger E-box-binding homeobox 1 …