Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

α‐Defensins in human innate immunity

RI Lehrer, W Lu - Immunological reviews, 2012 - Wiley Online Library
Defensins are small, multifunctional cationic peptides. They typically contain six conserved
cysteines whose three intramolecular disulfides stabilize a largely β‐sheet structure. This …

Massive gene presence-absence variation shapes an open pan-genome in the Mediterranean mussel

M Gerdol, R Moreira, F Cruz, J Gómez-Garrido… - Genome biology, 2020 - Springer
Abstract Background The Mediterranean mussel Mytilus galloprovincialis is an ecologically
and economically relevant edible marine bivalve, highly invasive and resilient to biotic and …

Antimicrobial peptides and copper (II) ions: Novel therapeutic opportunities

J Portelinha, SS Duay, SI Yu, K Heilemann… - Chemical …, 2021 - ACS Publications
The emergence of new pathogens and multidrug resistant bacteria is an important public
health issue that requires the development of novel classes of antibiotics. Antimicrobial …

Microbial diseases of bivalve mollusks: infections, immunology and antimicrobial defense

C Zannella, F Mosca, F Mariani, G Franci, V Folliero… - Marine drugs, 2017 - mdpi.com
A variety of bivalve mollusks (phylum Mollusca, class Bivalvia) constitute a prominent
commodity in fisheries and aquacultures, but are also crucial in order to preserve our …

Convergent evolution of defensin sequence, structure and function

TMA Shafee, FT Lay, TK Phan, MA Anderson… - Cellular and Molecular …, 2017 - Springer
Defensins are a well-characterised group of small, disulphide-rich, cationic peptides that are
produced by essentially all eukaryotes and are highly diverse in their sequences and …

Bioactive compounds from marine mussels and their effects on human health

U Grienke, J Silke, D Tasdemir - Food chemistry, 2014 - Elsevier
The consumption of marine mussels as popular seafood has increased steadily over the
past decades. Awareness of mussel derived molecules, that promote health, has contributed …

Immunity in molluscs: recognition and effector mechanisms, with a focus on bivalvia

M Gerdol, M Gomez-Chiarri, MG Castillo… - Advances in …, 2018 - Springer
The study of molluscan immune systems, in particular those of bivalve molluscs (eg, clams,
oysters, scallops, mussels), has experienced great growth in recent decades, mainly due to …

An updated molecular basis for mussel immunity

M Gerdol, P Venier - Fish & shellfish immunology, 2015 - Elsevier
Non-self recognition with the consequent tolerance or immune reaction is a crucial process
to succeed as living organisms. At the same time the interactions between host species and …

Sequence diversity and evolution of antimicrobial peptides in invertebrates

A Tassanakajon, K Somboonwiwat… - Developmental & …, 2015 - Elsevier
Antimicrobial peptides (AMPs) are evolutionarily ancient molecules that act as the key
components in the invertebrate innate immunity against invading pathogens. Several AMPs …