The pathogenesis underlining many neurodegenerative diseases remains incompletely
understood. The lack of effective biomarkers and disease preventative medicine demands …

Changes in protein expression levels and protein structure may indicate genomic mutations
and may be related to some diseases. Therefore, the precise quantification and …

Multiplexed detection of Alzheimer's disease (AD) core biomarkers is of great significance to
early diagnosis and personalized treatment of AD patients. Herein, we construct a robust …

This review focuses on recent developments in hybrid and nanostructured substrates for
SERS (surface-enhanced Raman scattering) studies. Thus substrates composed of at least …

Surface-enhanced Raman spectroscopy (SERS) has become a powerful tool for biosensing
applications owing to its fingerprint recognition, high sensitivity, multiplex detection, and …

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder and affects more
than 10% of the population aged over 65 worldwide. Despite considerable global efforts, AD …

Known as a main neural MAP (microtubule associated protein), tau protein contributes to
stabilizing microtubules involved in cellular transmission. Tau dysfunction is mainly …

Selective and sensitive detection of cancer biomarkers in serum samples is critical for early
diagnosis of cancer. Prostate specific antigen is an important biomarker of prostate cancer …

Ultrasensitive detection of chemicals and biological analytes in trace or single molecular
level is highly desirable in both scientific and technological fields, eg, analytical chemistry …

Detection of biomarkers is of vital importance in disease detection, management, and
monitoring of therapeutic efficacy. Extensive efforts have been devoted to the development …