Microwave-assisted multicomponent reactions in heterocyclic chemistry and mechanistic aspects

S Gulati, SE John… - Beilstein Journal of Organic …, 2021 - beilstein-journals.org
Microwave-assisted (MWA) multicomponent reactions (MCRs) have successfully emerged
as one of the useful tools in the synthesis of biologically relevant heterocycles. These …

Recent advances in the multicomponent synthesis of heterocycles using thiosemicarbazide

R Javahershenas, J Han, M Kazemi… - ChemistrySelect, 2024 - Wiley Online Library
This review provides an overview of the recent advances in the synthesis of diverse
heterocyclic compounds using thiosemicarbazide as a key building block via …

Microwave irradiated one pot, three component synthesis of a new series of hybrid coumarin based thiazoles: Antibacterial evaluation and molecular docking studies

S Mamidala, SR Peddi, RK Aravilli, PC Jilloju… - Journal of Molecular …, 2021 - Elsevier
A series of new coumarin based thiazoles were synthesized by the microwave irradiation of
thiocarbohydrazide, aldehydes and 3-(2-bromoacetyl) coumarins. Structures of all the …

A facile one-pot, three component synthesis of a new series of 1, 3, 4-thiadiazines: Anticancer evaluation and molecular docking studies

S Mamidala, V Vangala, SR Peddi… - Journal of Molecular …, 2021 - Elsevier
Abstract A series of new 1, 3, 4-thiadiazines were synthesized by the conventional method of
dehydroacetic acid, thiocarbohydrazide and substituted phenacyl bromides or substituted 3 …

A facile one-pot, three-component synthesis of a new series of thiazolyl pyrazole carbaldehydes: In vitro anticancer evaluation, in silico ADME/T, and molecular …

S Mamidala, RK Aravilli, G Ramesh, S Khajavali… - Journal of Molecular …, 2021 - Elsevier
A series of thiazolyl pyrazole carbaldehydes (4a-n) were synthesized by conventional
method using thiosemicarbazide, substituted phenacyl bromides, substituted 3 …

In Sight into innovative cancer therapeutic approach based on nanotechnology: Chitosan (CS)/Polyvinyl alcohol (PVA) films loaded with synthesized bisthiazole …

M Ayman, SM Gomha, MA Abdallah… - Egyptian Journal of …, 2023 - journals.ekb.eg
Acetyl thiazole thiosemicarbazone 3 was used as key intermediate for preparation of novel
series of thiazolylhydrazono thiazole derivatives via reaction of 3 with two types of …

Application of phenacyl bromide analogs as a versatile organic intermediate for the synthesis of heterocyclic compounds via multicomponent reactions

R Javahershenas - Molecular Diversity, 2023 - Springer
Due to the increased interest in heterocyclic compounds over the past decade, many
pharmaceutical and organic chemists have explored the synthesis of various materials …

Development in the Synthesis of Bioactive Thiazole-Based Heterocyclic Hybrids Utilizing Phenacyl Bromide

G Kumari, S Dhillon, P Rani, M Chahal, DK Aneja… - ACS …, 2024 - ACS Publications
Heterocyclic hybrid frameworks represent a burgeoning domain within the realms of drug
discovery and medicinal chemistry, attracting considerable attention in recent years …

Microwave-assisted domino cyclization reactions

YB Wagh, DS Dalal - Current Microwave Chemistry, 2021 - benthamdirect.com
Background: Microwave-assisted domino cyclization reactions have attracted great interest
for researchers to synthesize complex compounds in shorter times with increased yields …

Design and synthesis of new thiazoles by microwave-assisted method: evaluation as an anti-breast cancer agents and molecular docking studies

S Mamidala, VS Mudigunda, SR Peddi… - Synthetic …, 2020 - Taylor & Francis
A series of novel thiazole analogues were designed and synthesized by the microwave-
assisted multicomponent reaction of thiocarbohydrazide, aldehydes with substituted …