New approaches to visual rehabilitation for cortical blindness: outcomes and putative mechanisms

A Das, KR Huxlin - The Neuroscientist, 2010 - journals.sagepub.com
Cortical blindness is a chronic loss of vision following damage to the primary visual cortex
(V1) or its postchiasmal afferents. Such damage is followed by a brief period of spontaneous …

Rehabilitation of visual perception in cortical blindness

EL Saionz, A Busza, KR Huxlin - Handbook of clinical neurology, 2022 - Elsevier
Blindness is a common sequela after stroke affecting the primary visual cortex, presenting as
a contralesional, homonymous, visual field cut. This can occur unilaterally or, less …

Correction of distortion in flattened representations of the cortical surface allows prediction of V1-V3 functional organization from anatomy

NC Benson, OH Butt, DH Brainard… - PLoS computational …, 2014 - journals.plos.org
Several domains of neuroscience offer map-like models that link location on the cortical
surface to properties of sensory representation. Within cortical visual areas V1, V2, and V3 …

Spared perilesional V1 activity underlies training-induced recovery of luminance detection sensitivity in cortically-blind patients

A Barbot, A Das, MD Melnick, MR Cavanaugh… - Nature …, 2021 - nature.com
Damage to the primary visual cortex (V1) causes homonymous visual-field loss long
considered intractable. Multiple studies now show that perceptual training can restore visual …

Different spatial scales of shape similarity representation in lateral and ventral LOC

DM Drucker, GK Aguirre - Cerebral Cortex, 2009 - academic.oup.com
We investigated the relationship between stimulus similarity for a set of parameterized
shapes and the spatial scale of neural representation within subregions of the lateral …

A detection theoretic explanation of blindsight suggests a link between conscious perception and metacognition

Y Ko, H Lau - … Transactions of the Royal Society B …, 2012 - royalsocietypublishing.org
Blindsight refers to the rare ability of V1-damaged patients to perform visual tasks such as
forced-choice discrimination, even though these patients claim not to consciously see the …

The nature of consciousness in the visually deprived brain

R Kupers, P Pietrini, E Ricciardi, M Ptito - Frontiers in psychology, 2011 - frontiersin.org
Vision plays a central role in how we represent and interact with the world around us. The
primacy of vision is structurally imbedded in cortical organization as about one-third of the …

Fast and reversible neural inactivation in macaque cortex by optogenetic stimulation of GABAergic neurons

A De, Y El-Shamayleh, GD Horwitz - Elife, 2020 - elifesciences.org
Optogenetic techniques for neural inactivation are valuable for linking neural activity to
behavior but they have serious limitations in macaques. To achieve powerful and temporally …

The primary visual cortex, and feedback to it, are not necessary for conscious vision

DH Ffytche, S Zeki - Brain, 2011 - academic.oup.com
A compelling single case report of visual awareness (visual qualia) without primary visual
cortex would be sufficient to refute the hypothesis that the primary visual cortex and the back …

Structural and functional changes across the visual cortex of a patient with visual form agnosia

H Bridge, OM Thomas, L Minini… - Journal of …, 2013 - Soc Neuroscience
Loss of shape recognition in visual-form agnosia occurs without equivalent losses in the use
of vision to guide actions, providing support for the hypothesis of two visual systems (for …