Current methods to differentiate cardiomyocytes from human pluripotent stem cells (PSCs)
inadequately recapitulate complete development and result in PSC-derived cardiomyocytes …

Osteoarthritis is a common age-related joint degenerative disease. Pain, swelling, brief
morning stiffness, and functional limitations are its main characteristics. There are still no …

The WNT/β‐catenin pathway is a master regulator of cardiac development and growth, and
its activity is low in healthy adult hearts. However, even this low activity is essential for …

One of the biggest challenges in tissue engineering and regenerative medicine is to
incorporate a functioning vasculature to overcome the consequences of a lack of oxygen …

Abstract Background Cardiac stem cells (CSCs) transplantation has been regarded as an
optimal therapeutic approach for cardiovascular disease. However, inferior survival and low …

Introduction: Diabetes mellitus (DM) affects over 422 million people globally. Patients with
DM are subject to a myriad of complications, of which diabetic foot ulcers (DFUs) are the …

Cardiac function highly relies on sufficient energy supply. Perturbations in myocardial
energy metabolism play a causative role in cardiac pathogenesis. Accumulating evidence …

Organic semiconductors are constantly gaining interest in regenerative medicine. Their
tunable physico-chemical properties, including electrical conductivity, are very promising for …

Melatonin, a molecule involved in the regulation of circadian rhythms, has protective effects
against myocardial injuries. However, its capability to regulate the maturation of cardiac …

Congenital heart disease (CHD) affects a considerable number of children and adults
worldwide. This implicates not only developmental disorders, high mortality, and reduced …