Frontiers in the treatment of glioblastoma: Past, present and emerging

TI Janjua, P Rewatkar, A Ahmed-Cox, I Saeed… - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …

Recent developments in solid lipid nanoparticle and surface-modified solid lipid nanoparticle delivery systems for oral delivery of phyto-bioactive compounds in …

P Ganesan, P Ramalingam… - International journal …, 2018 - Taylor & Francis
Solid lipid nanoparticle (SLN) delivery systems have a wide applicability in the delivery of
phyto-bioactive compounds to treat various chronic diseases, including diabetes, cancer …

Photodynamic therapy for glioblastoma: illuminating the path toward clinical applicability

D Bhanja, H Wilding, A Baroz, M Trifoi, G Shenoy… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma (GBM) is the most common adult brain cancer. Despite
extensive treatment protocols, all glioblastomas are eventually fatal. Photodynamic therapy …

Chemistry, biosynthesis and pharmacology of sarsasapogenin: a potential natural steroid molecule for new drug design, development and therapy

NH Mustafa, M Sekar, S Fuloria, MY Begum, SH Gan… - Molecules, 2022 - mdpi.com
Sarsasapogenin is a natural steroidal sapogenin molecule obtained mainly from
Anemarrhena asphodeloides Bunge. Among the various phytosteroids present …

Cyclooxygenase-2 in glioblastoma multiforme

J Qiu, Z Shi, J Jiang - Drug discovery today, 2017 - Elsevier
Highlights•Current treatment for glioblastoma fails to provide sufficient therapeutic
outcomes.•Overexpressed cyclooxygenase-2 (COX-2) contributes to the glioblastoma …

Therapeutic applications of curcumin nanomedicine formulations in cardiovascular diseases

B Salehi, ML Del Prado-Audelo, H Cortés… - Journal of clinical …, 2020 - mdpi.com
Cardiovascular diseases (CVD) compromises a group of heart and blood vessels disorders
with high impact on human health and wellbeing. Curcumin (CUR) have demonstrated …

[HTML][HTML] Tilianin: A potential natural lead molecule for new drug design and development for the treatment of cardiovascular disorders

FS Khattulanuar, M Sekar, S Fuloria, SH Gan… - Molecules, 2022 - mdpi.com
Cardiovascular disorders (CVDs) are the leading risk factor for death worldwide, and
research into the processes and treatment regimens has received a lot of attention. Tilianin …

Resveratrol Suppresses Epithelial‐Mesenchymal Transition in GBM by Regulating Smad‐Dependent Signaling

Y Song, Y Chen, Y Li, X Lyu, J Cui… - BioMed Research …, 2019 - Wiley Online Library
Glioblastoma (GBM) is the most common and malignant intracranial tumor in adults. Despite
continuous improvements in diagnosis and therapeutic method, the prognosis is still far …

Effects of curcumin-loaded PLGA nanoparticles on the RG2 rat glioma model

M Orunoğlu, A Kaffashi, SB Pehlivan, S Şahin… - Materials Science and …, 2017 - Elsevier
Background Curcumin, the active ingredient of turmeric, has a remarkable antitumor activity
against various cancers, including glioblastoma. However, it has poor absorption and low …

Resveratrol targeting of AKT and p53 in glioblastoma and glioblastoma stem-like cells to suppress growth and infiltration

PA Clark, S Bhattacharya, A Elmayan… - Journal of …, 2017 - thejns.org
OBJECTIVE Glioblastoma multiforme (GBM) is an aggressive brain cancer with median
survival of less than 2 years with current treatment. Glioblastomas exhibit extensive …