Genetic engineering of bacteriophages: Key concepts, strategies, and applications

W Hussain, X Yang, M Ullah, H Wang, A Aziz… - Biotechnology …, 2023 - Elsevier
Bacteriophages are the most abundant biological entity in the world and hold a tremendous
amount of unexplored genetic information. Since their discovery, phages have drawn a great …

Bacteriophage T4 as a nanovehicle for delivery of genes and therapeutics into human cells

VB Rao, J Zhu - Current opinion in virology, 2022 - Elsevier
The ability to deliver therapeutic genes and biomolecules into a human cell and restore a
defective function has been the holy grail of medicine. Adeno-associated viruses and …

Closing the door with CRISPR: genome editing of CCR5 and CXCR4 as a potential curative solution for HIV

JJ Freen-van Heeren - BioTech, 2022 - mdpi.com
Human immunodeficiency virus (HIV) infection can be controlled by anti-retroviral therapy.
Suppressing viral replication relies on life-long medication, but anti-retroviral therapy is not …

Investigating the role of peptides in effective therapies against cancer

R Naeimi, A Bahmani, S Afshar - Cancer Cell International, 2022 - Springer
Early diagnosis and effective treatment of cancer are challenging. To diagnose and treat
cancer effectively and to overcome these challenges, fundamental innovations in traditional …

Application of CRISPR/Cas genomic editing tools for HIV therapy: toward precise modifications and multilevel protection

A Maslennikova, D Mazurov - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Although highly active antiretroviral therapy (HAART) can robustly control human
immunodeficiency virus (HIV) infection, the existence of latent HIV in a form of proviral DNA …

What to expect from COVID-19 and from COVID-19 vaccine for expecting or lactating women

R Gangi, A Corrias, R Pintus, MA Marcialis, V Fanos - Pediatric Reports, 2022 - mdpi.com
Recent studies identified pregnancy as a high-risk condition for the development of maternal-
fetal complications in the case of the SARS-CoV-2 infection. Therefore, the scientific …

Comprehensive highlights of the universal efforts towards the development of COVID-19 vaccine

RA Shaik, MS Ahmad, M Alzahrani, NAN Alzerwi… - Vaccines, 2022 - mdpi.com
The world has taken proactive measures to combat the pandemic since the coronavirus
disease 2019 (COVID-19) outbreak, which was caused by severe acute respiratory …

[PDF][PDF] Comprehensive Highlights of the Universal Efforts towards the Development of COVID-19 Vaccine. Vaccines 2022, 10, 1689

RA Shaik, MS Ahmad, M Alzahrani, NAN Alzerwi… - 2022 - researchgate.net
The world has taken proactive measures to combat the pandemic since the coronavirus
disease 2019 (COVID-19) outbreak, which was caused by severe acute respiratory …