Antimicrobial resistance in bacterial pathogens is a worldwide challenge leading high
morbidity and mortality in clinical settings. Multidrug resistant patterns in gram-positive and …

In the 1980s, Gram-negative pathogens appeared to have been beaten by oxyimino-
cephalosporins, carbapenems, and fluoroquinolones. Yet these pathogens have fought …

Since antibiotics were first used, each new introduced class has been followed by a global
wave of emergent resistance, largely originating in Europe and North America where they …

Resistance trends have changed greatly over the 14 years (1997–2011) whilst I was
Director of the UK Antibiotic Resistance Monitoring and Reference Laboratory (ARMRL) …

Infectious diseases due to Gram-negative bacteria are a leading cause of morbidity and
mortality worldwide. Antimicrobial agents represent one major therapeutic tools implicated to …

Objectives There is considerable evidence linking antibiotic usage to bacterial resistance.
Intervention strategies are needed to contain antibiotic use and thereby resistance. To plan …

Background: The emergence of antibiotic resistance among bacterial pathogens in the
hospital and community has increased the concern to the health-care providers due to the …

The numbers of infections caused by Gram-negative bacteria (GNB) that produce extended-
spectrum beta-lactamases (ESBLs) and those that are carbapenem resistant, especially …

Background We performed this study 1) to determine the prevalence of community-
associated extended spectrum beta-lactamase producing Enterobacteriaceae (ESBLPE) …

Introduction: Klebsiella pneumoniae-associated liver abscess (KPLA) is often accompanied
by extrahepatic complications. We investigated the clinical features and outcomes of …