Sex differences in endothelial function important to vascular health and overall cardiovascular disease risk across the lifespan

AE Stanhewicz, MM Wenner… - American Journal of …, 2018 - journals.physiology.org
Diseases of the cardiovascular system are the leading cause of morbidity and mortality in
men and women in developed countries, and cardiovascular disease (CVD) is becoming …

Worse progression of COVID‐19 in men: is testosterone a key factor?

VA Giagulli, E Guastamacchia, T Magrone, E Jirillo… - …, 2021 - Wiley Online Library
Background The novel severe acute respiratory syndrome coronavirus (SARS‐CoV‐2)
disease 2019 (COVID‐19) seems to have a worse clinical course among infected men …

Endogenous testosterone and mortality in men: a systematic review and meta-analysis

AB Araujo, JM Dixon, EA Suarez… - The Journal of …, 2011 - academic.oup.com
Context: Low testosterone levels have been associated with outcomes that reduce survival
in men. Objective: Our objective was to perform a systematic review and meta-analysis of …

Sex differences in vascular physiology and pathophysiology: estrogen and androgen signaling in health and disease

AC Boese, SC Kim, KJ Yin, JP Lee… - American Journal of …, 2017 - journals.physiology.org
Sex differences between women and men are often overlooked and underappreciated when
studying the cardiovascular system. It has been long assumed that men and women are …

The decline of androgen levels in elderly men and its clinical and therapeutic implications

JM Kaufman, A Vermeulen - Endocrine reviews, 2005 - academic.oup.com
Aging in men is accompanied by a progressive, but individually variable decline of serum
testosterone production, more than 20% of healthy men over 60 yr of age presenting with …

Molecular and cellular basis of cardiovascular gender differences

ME Mendelsohn, RH Karas - Science, 2005 - science.org
Cardiovascular diseases (CVDs), the major cause of morbidity and mortality for both men
and women, occur uncommonly in premenopausal women, but their incidence rises sharply …

Sex differences in autoimmune disease from a pathological perspective

DL Fairweather, S Frisancho-Kiss, NR Rose - The American journal of …, 2008 - Elsevier
Autoimmune diseases affect∼ 8% of the population, 78% of whom are women. The reason
for the high prevalence in women is unclear. Women are known to respond to infection …

Erectile dysfunction and subsequent cardiovascular disease

IM Thompson, CM Tangen, PJ Goodman… - Jama, 2005 - jamanetwork.com
ContextThe risk factors for cardiovascular disease and erectile dysfunction are similar.
ObjectiveTo examine the association of erectile dysfunction and subsequent cardiovascular …

Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC …

KT Khaw, M Dowsett, E Folkerd, S Bingham… - Circulation, 2007 - Am Heart Assoc
Background—The relation between endogenous testosterone concentrations and health in
men is controversial. Methods and Results—We examined the prospective relationship …

Comprehensive review of cardiovascular toxicity of drugs and related agents

P Mladěnka, L Applová, J Patočka… - Medicinal research …, 2018 - Wiley Online Library
Cardiovascular diseases are a leading cause of morbidity and mortality in most developed
countries of the world. Pharmaceuticals, illicit drugs, and toxins can significantly contribute to …