Mechanisms of ovarian aging

SU Park, L Walsh, KM Berkowitz - Reproduction, 2021 - rep.bioscientifica.com
Ovarian aging in women correlates with the progressive loss of both the number and quality
of oocytes. When these processes occur early or are accelerated, their clinical correlates are …

Mechanisms of ovarian aging in women: a review

X Wang, L Wang, W Xiang - Journal of Ovarian Research, 2023 - Springer
Ovarian aging is a natural and physiological aging process characterized by loss of quantity
and quality of oocyte or follicular pool. As it is generally accepted that women are born with a …

Premature ovarian insufficiency (POI) and autoimmunity-an update appraisal

M Kirshenbaum, R Orvieto - Journal of assisted reproduction and genetics, 2019 - Springer
Purpose Primary ovarian insufficiency (POI) represents ovarian dysfunction related to very
early aging of the ovaries. While the cause of POI in a majority of clinical cases remains …

Human mesenchymal stem cell treatment of premature ovarian failure: new challenges and opportunities

YX Fu, J Ji, F Shan, J Li, R Hu - Stem Cell Research & Therapy, 2021 - Springer
Premature ovarian failure (POF) is one of the common disorders found in women leading to
1% female infertility. Clinical features of POF are hypoestrogenism or estrogen deficiency …

Reactivating ovarian function through autologous platelet-rich plasma intraovarian infusion: pilot data on premature ovarian insufficiency, perimenopausal …

K Sfakianoudis, M Simopoulou, S Grigoriadis… - Journal of clinical …, 2020 - mdpi.com
Intraovarian platelet-rich plasma (PRP) infusion was recently introduced in the context of
addressing ovarian insufficiency. Reporting on its effectiveness prior to adopting in clinical …

Efficient metabolic fingerprinting of follicular fluid encodes ovarian reserve and fertility

J Wu, C Liang, X Wang, Y Huang, W Liu… - Advanced …, 2023 - Wiley Online Library
Ovarian reserve (OR) and fertility are critical in women's healthcare. Clinical methods for
encoding OR and fertility rely on the combination of tests, which cannot serve as a multi …

Fertility after curative therapy for sickle cell disease: a comprehensive review to guide care

RS Nickel, JY Maher, MH Hsieh, MF Davis… - Journal of clinical …, 2022 - mdpi.com
Curative therapy for sickle cell disease (SCD) currently requires gonadotoxic conditioning
that can impair future fertility. Fertility outcomes after curative therapy are likely affected by …

New insights into the genetic basis of premature ovarian insufficiency: novel causative variants and candidate genes revealed by genomic sequencing

S Jaillard, K Bell, L Akloul, K Walton, K McElreavy… - Maturitas, 2020 - Elsevier
Ovarian deficiency, including premature ovarian insufficiency (POI) and diminished ovarian
reserve (DOR), represents one of the main causes of female infertility. POI is a genetically …

Bone marrow mesenchymal stem cells in premature ovarian failure: Mechanisms and prospects

Y Huang, M Zhu, Z Liu, R Hu, F Li, Y Song… - Frontiers in …, 2022 - frontiersin.org
Premature ovarian failure (POF) is a common female reproductive disorder and
characterized by menopause, increased gonadotropin levels and estrogen deficiency before …

Synthetic phenolic antioxidants and their metabolites in follicular fluid and association with diminished ovarian reserve: A case–control study

Y Hao, Y Wang, L Yan, X Xu, D Chen… - Environmental Health …, 2023 - ehp.niehs.nih.gov
Background: Diminished/decreased ovarian reserve (DOR) is a disorder of ovarian function,
which severely affects women's reproductive health. Accumulating evidence has found that …