Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in
obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than …

Obesity, a social problem worldwide, is characterized by an increase in body weight that
results in excessive fat accumulation. Obesity is a major cause of morbidity and mortality and …

To fulfill its role as the major energy-storing tissue, adipose has several unique properties
that cannot be seen in any other organ, including an almost unlimited capacity to expand in …

The rise in the incidence of obesity has led to a major interest in the biology of white adipose
tissue. The tissue is a major endocrine and signaling organ, with adipocytes, the …

The classical perception of adipose tissue as a storage place of fatty acids has been
replaced over the last years by the notion that adipose tissue has a central role in lipid and …

Obesity is the hallmark of the metabolic syndrome and predisposes patients to the
development of major chronic metabolic diseases including type 2 diabetes mellitus …

Overweight and obesity are health problems of epidemic proportions, increasing the risk not
only of cardiovascular disease and type 2 diabetes mellitus but also of various types of …

BACKGROUND Data from studies conducted in rodent models have shown that decreased
adipose tissue (AT) oxygenation is involved in the pathogenesis of obesity-induced insulin …

Chronic inflammation and reduced adiponectin are widely observed in the white adipose
tissue in obesity. However, the cause of the changes remains to be identified. In this study …

Background—Inflammation in adipose tissue has been implicated in vascular dysfunction,
but the local mechanisms by which this occurs are unknown. Methods and Results—Small …