Ferroptosis as a mechanism of non-ferrous metal toxicity

M Aschner, AV Skalny, AC Martins, AI Sinitskii… - Archives of …, 2022 - Springer
Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …

[HTML][HTML] Disease-associated metabolic pathways affected by heavy metals and metalloid

Z Haidar, K Fatema, SS Shoily, AA Sajib - Toxicology reports, 2023 - Elsevier
Increased exposure to environmental heavy metals and metalloids and their associated
toxicities has become a major threat to human health. Hence, the association of these …

Transgenerational effects in DNA methylation, genotoxicity and reproductive phenotype by chronic arsenic exposure

LE Nava-Rivera, ND Betancourt-Martínez… - Scientific reports, 2021 - nature.com
An emerging concern is the influences of early life exposure to environmental toxicants on
offspring characteristics in later life. Since recent evidence suggests a transgenerational …

Is arsenic exposure a risk factor for metabolic syndrome? a review of the potential mechanisms

P Pánico, M Velasco, AM Salazar, A Picones… - Frontiers in …, 2022 - frontiersin.org
Exposure to arsenic in drinking water is a worldwide health problem. This pollutant is
associated with increased risk of developing chronic diseases, including metabolic …

DNA damage resulting from human endocrine disrupting chemical exposure: Genotoxicity, detection and dietary phytochemical intervention

X Li, N Zang, N Zhang, L Pang, L Lv, X Meng, X Lv… - Chemosphere, 2023 - Elsevier
In recent years, exposure to endocrine disrupting chemicals (EDCs) has posed an
increasing threat to human health. EDCs are major risk factors in the occurrence and …

Integrated miRNA-mRNA analysis reveals the dysregulation of lipid metabolism in mouse liver induced by developmental arsenic exposure

X Chen, R Wu, H Wu, Y Hu, H Wang, J Fu, J Pi… - Journal of Hazardous …, 2023 - Elsevier
Developmental arsenic exposure leads to increased susceptibility to liver diseases including
nonalcoholic fatty liver diseases, but the mechanism is incompletely understood. In this …

Metabolic derangement by Arsenic: a review of the mechanisms

K Bibha, TM Akhigbe, MA Hamed… - Biological Trace Element …, 2024 - Springer
Studies have implicated arsenic exposure in various pathological conditions, including
metabolic disorders, which have become a global phenomenon, affecting developed …

Inter‐and Transgenerational Effects of Paternal Exposure to Inorganic Arsenic

Y Gong, Y Xue, X Li, Z Zhang, W Zhou… - Advanced …, 2021 - Wiley Online Library
The rise of metabolic disorders in modern times is mainly attributed to the environment.
However, heritable effects of environmental chemicals on mammalian offsprings' metabolic …

[HTML][HTML] Protective effects of curcumin on ATO-induced nephrotoxicity in ducks in relation to suppressed autophagy, apoptosis and dyslipidemia by regulating …

S Wu, W Yu, X Jiang, R Huang, X Zhang, J Lan… - Ecotoxicology and …, 2021 - Elsevier
Arsenic trioxide (ATO) has been known as common environmental pollution, and is deemed
to a threat to global public health. Curcumin (Cur) is a phytoconstituent, which has been …

Sex differences in paternal arsenic-induced intergenerational metabolic effects are mediated by estrogen

Y Xue, Y Gong, X Li, F Peng, G Ding, Z Zhang, J Shi… - Cell & Bioscience, 2023 - Springer
Background Gene-environment interactions contribute to metabolic disorders such as
diabetes and dyslipidemia. In addition to affecting metabolic homeostasis directly, drugs and …