Imaging and photodynamic therapy: mechanisms, monitoring, and optimization

JP Celli, BQ Spring, I Rizvi, CL Evans… - Chemical …, 2010 - ACS Publications
The purpose of this review is to present the current state of the role of imaging in
photodynamic therapy (PDT). For the reader to fully appreciate the context of the discussions …

Like a bolt from the blue: phthalocyanines in biomedical optics

N Sekkat, H van den Bergh, T Nyokong, N Lange - Molecules, 2011 - mdpi.com
The purpose of this review is to compile preclinical and clinical results on phthalocyanines
(Pcs) as photosensitizers (PS) for Photodynamic Therapy (PDT) and contrast agents for …

Highly Efficient Drug Delivery with Gold Nanoparticle Vectors for in Vivo Photodynamic Therapy of Cancer

Y Cheng, AC Samia, JD Meyers… - Journal of the …, 2008 - ACS Publications
A highly efficient drug vector for photodynamic therapy (PDT) drug delivery was developed
by synthesizing PEGylated gold nanoparticle conjugates, which act as a water-soluble and …

Hyperspectral imaging and quantitative analysis for prostate cancer detection

H Akbari, LV Halig, DM Schuster… - … of biomedical optics, 2012 - spiedigitallibrary.org
Hyperspectral imaging (HSI) is an emerging modality for various medical applications. Its
spectroscopic data might be able to be used to noninvasively detect cancer. Quantitative …

Targeted iron-oxide nanoparticle for photodynamic therapy and imaging of head and neck cancer

D Wang, B Fei, LV Halig, X Qin, Z Hu, H Xu, YA Wang… - ACS …, 2014 - ACS Publications
Photodynamic therapy (PDT) is a highly specific anticancer treatment modality for various
cancers, particularly for recurrent cancers that no longer respond to conventional anticancer …

Delivery and efficacy of a cancer drug as a function of the bond to the gold nanoparticle surface

Y Cheng, AC Samia, J Li, ME Kenney, A Resnick… - Langmuir, 2010 - ACS Publications
In this feature article, gold nanoparticle conjugates loaded with phthalocyanine-based PDT
drugs are prepared and tested for delivery efficiency and PDT efficacy on HeLa cancer cells …

Computer-aided detection of prostate cancer with MRI: technology and applications

L Liu, Z Tian, Z Zhang, B Fei - Academic radiology, 2016 - Elsevier
One in six men will develop prostate cancer in his lifetime. Early detection and accurate
diagnosis of the disease can improve cancer survival and reduce treatment costs. Recently …

Influence of nanoparticle materials on the photophysical behavior of phthalocyanines

T Nyokong, E Antunes - Coordination Chemistry Reviews, 2013 - Elsevier
This review presents recent data on the photophysical behavior of phthalocyanines when
conjugated to quantum dots, gold and magnetic nanoparticles. In some cases such …

A cell-targeted photodynamic nanomedicine strategy for head and neck cancers

A Master, A Malamas, R Solanki… - Molecular …, 2013 - ACS Publications
Photodynamic therapy (PDT) holds great promise for the treatment of head and neck (H&N)
carcinomas where repeated loco-regional therapy often becomes necessary due to the …

3D ultrasound image segmentation using wavelet support vector machines

H Akbari, B Fei - Medical physics, 2012 - Wiley Online Library
Purpose: Transrectal ultrasound (TRUS) imaging is clinically used in prostate biopsy and
therapy. Segmentation of the prostate on TRUS images has many applications. In this study …