Microbial transitions from health to disease

S Joseph, MA Curtis - Periodontology 2000, 2021 - Wiley Online Library
Recent advances in our understanding of the microbial populations that colonize the human
mouth, their acquisition, interdependency, and coevolution with the host, bring a different …

Critical review of 16S rRNA gene sequencing workflow in microbiome studies: From primer selection to advanced data analysis

A Regueira‐Iglesias, C Balsa‐Castro… - Molecular Oral …, 2023 - Wiley Online Library
The multi‐batch reanalysis approach of jointly reevaluating gene/genome sequences from
different works has gained particular relevance in the literature in recent years. The large …

The role of bacterial biofilms in dental caries and periodontal and peri-implant diseases: a historical perspective

APV Colombo, ACR Tanner - Journal of dental research, 2019 - journals.sagepub.com
Over the last hundred years, groundbreaking research in oral microbiology has provided a
broad and deep understanding about the oral microbiome, its interactions with our body …

Machine learning methods for microbiome studies

J Namkung - Journal of Microbiology, 2020 - Springer
Researches on the microbiome have been actively conducted worldwide and the results
have shown human gut bacterial environment significantly impacts on immune system …

Macrophage immunomodulation in chronic osteolytic diseases—The case of periodontitis

C Sima, A Viniegra, M Glogauer - Journal of leukocyte biology, 2019 - academic.oup.com
Periodontitis (PD) is a chronic osteolytic disease that shares pathogenic inflammatory
features with other conditions associated with nonresolving inflammation. A hallmark of PD …

Who is in the driver's seat? Parvimonas micra: An understudied pathobiont at the crossroads of dysbiotic disease and cancer

DL Higashi, MC Krieger, H Qin, Z Zou… - Environmental …, 2023 - Wiley Online Library
Recent advances in our understanding of microbiome composition at sites of inflammatory
dysbiosis have triggered a substantial interest in a variety of historically understudied …

Subgingival microbiome and clinical periodontal status in an elderly cohort: The WHICAP ancillary study of oral health

PN Papapanou, H Park, B Cheng… - Journal of …, 2020 - Wiley Online Library
Background There is a sparsity of data describing the periodontal microbiome in elderly
individuals. We analyzed the association of subgingival bacterial profiles and clinical …

Microbial Complexes and Caries in 17-Year-Olds with and without Streptococcus mutans

L Eriksson, P Lif Holgerson, A Esberg… - Journal of Dental …, 2018 - journals.sagepub.com
Streptococcus mutans is a key bacterial species in the caries process, which affects> 90% of
the population worldwide. However, other acidogenic and aciduric/acidophilic species may …

Bacterial biofilm composition in healthy subjects with and without caries experience.

K Schoilew, H Ueffing, A Dalpke, B Wolff… - Journal of oral …, 2019 - Taylor & Francis
Objective: The composition of the oral microbiome differs distinctively between subjects with
and without active caries. Still, caries research has mainly been focused on states of …

Metagenomic sequencing provides new insights into the subgingival bacteriome and aetiopathology of periodontitis

E Ng, JRH Tay, P Balan, MMA Ong… - Journal of …, 2021 - Wiley Online Library
Abstract “Open‐ended” molecular techniques such as 16S rRNA sequencing have revealed
that the oral bacteriome of subgingival plaque is more diverse than originally thought. 16S …