Scleral structure and biomechanics

C Boote, IA Sigal, R Grytz, Y Hua, TD Nguyen… - Progress in retinal and …, 2020 - Elsevier
As the eye's main load-bearing connective tissue, the sclera is centrally important to vision.
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …

Lamina cribrosa in glaucoma

JC Downs, CA Girkin - Current opinion in ophthalmology, 2017 - journals.lww.com
Lamina cribrosa in glaucoma : Current Opinion in Ophthalmology Lamina cribrosa in glaucoma :
Current Opinion in Ophthalmology Log in or Register Subscribe to journalSubscribe Get new …

DRUNET: a dilated-residual U-Net deep learning network to segment optic nerve head tissues in optical coherence tomography images

SK Devalla, PK Renukanand, BK Sreedhar… - Biomedical optics …, 2018 - opg.optica.org
Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex
morphological changes with the development and progression of glaucoma, their …

Comprehensive review on the use of artificial intelligence in ophthalmology and future research directions

N Anton, B Doroftei, S Curteanu, L Catãlin, OD Ilie… - Diagnostics, 2022 - mdpi.com
Background: Having several applications in medicine, and in ophthalmology in particular,
artificial intelligence (AI) tools have been used to detect visual function deficits, thus playing …

Eye-specific IOP-induced displacements and deformations of human lamina cribrosa

IA Sigal, JL Grimm, NJ Jan, K Reid… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: To measure high-resolution eye-specific displacements and deformations induced
within the human LC microstructure by an acute increase in IOP. Methods.: Six eyes from …

Glaucoma-related changes in the mechanical properties and collagen micro-architecture of the human sclera

B Coudrillier, JK Pijanka, JL Jefferys, A Goel… - PloS one, 2015 - journals.plos.org
Objective The biomechanical behavior of the sclera determines the level of mechanical
insult from intraocular pressure to the axons and tissues of the optic nerve head, as is of …

Biomechanics of the posterior eye: a critical role in health and disease

IC Campbell, B Coudrillier… - Journal of …, 2014 - asmedigitalcollection.asme.org
The posterior eye is a complex biomechanical structure. Delicate neural and vascular
tissues of the retina, choroid, and optic nerve head that are critical for visual function are …

In vivo 3-dimensional strain mapping confirms large optic nerve head deformations following horizontal eye movements

X Wang, MR Beotra, TA Tun… - … & visual science, 2016 - iovs.arvojournals.org
Purpose: To measure lamina cribrosa (LC) strains (deformations) following abduction and
adduction in healthy subjects and to compare them with those resulting from a relatively high …

Translating ocular biomechanics into clinical practice: current state and future prospects

MJA Girard, WJ Dupps, M Baskaran… - Current eye …, 2015 - Taylor & Francis
Biomechanics is the study of the relationship between forces and function in living
organisms and is thought to play a critical role in a significant number of ophthalmic …

In vivo 3-dimensional strain mapping of the optic nerve head following intraocular pressure lowering by trabeculectomy

MJA Girard, MR Beotra, KS Chin, A Sandhu, M Clemo… - Ophthalmology, 2016 - Elsevier
Purpose To map the 3-dimensional (3D) strain of the optic nerve head (ONH) in vivo after
intraocular pressure (IOP) lowering by trabeculectomy (TE) and to establish associations …