Chemokine function in periodontal disease and oral cavity cancer

SE Sahingur, WA Yeudall - Frontiers in immunology, 2015 - frontiersin.org
The chemotactic cytokines, or chemokines, comprise a superfamily of polypeptides with a
wide range of activities that include recruitment of immune cells to sites of infection and …

[PDF][PDF] Periodontitis and oral cancer-current concepts of the etiopathogenesis

S Irani, I Barati, M Badiei - Oncology reviews, 2020 - frontierspartnerships.org
Gingival tissues are attacked by oral pathogens which can induce inflammatory reactions.
The immune-inflammatory responses play essential roles in the patient susceptibility to …

Matrix metalloproteinases and myeloperoxidase in gingival crevicular fluid provide site‐specific diagnostic value for chronic periodontitis

JM Leppilahti, PA Hernández‐Ríos… - Journal of clinical …, 2014 - Wiley Online Library
Aim To identify the diagnostic accuracy of gingival crevicular fluid (GCF) candidate
biomarkers to discriminate periodontitis from the inflamed and healthy sites, and to compare …

Development of an in vitroperiodontal biofilm model for assessing antimicrobial and host modulatory effects of bioactive molecules

E Millhouse, A Jose, L Sherry, DF Lappin, N Patel… - BMC oral health, 2014 - Springer
Background Inflammation within the oral cavity occurs due to dysregulation between
microbial biofilms and the host response. Understanding how different oral hygiene products …

CXCL5, CXCL8, and CXCL10 regulation by bacteria and mechanical forces in periodontium

B Rath-Deschner, S Memmert, A Damanaki… - Annals of Anatomy …, 2021 - Elsevier
Objective The aim of the present study was to evaluate the expressions of CXCL5, CXCL8,
and CXCL10 in periodontal cells and tissues in response to microbial signals and/or …

Is there an interaction between polycystic ovary syndrome and gingival inflammation?

Ö Özçaka, BÖ Ceyhan, A Akcali… - Journal of …, 2012 - Wiley Online Library
Background: The aim of this study is to evaluate the gingival crevicular fluid (GCF), saliva,
and serum concentrations of tumor necrosis factor‐α (TNF‐α), TNF‐α receptor‐1 (TNF‐αR1) …

Antibiofilm peptides against oral biofilms

Z Wang, Y Shen, M Haapasalo - Journal of Oral Microbiology, 2017 - Taylor & Francis
The oral cavity is a major entry point for bacteria and other microorganisms. Oral biofilms are
formed by mixed communities of microorganisms embedded in an exopolysaccharide …

The role of periodontitis in cancer development, with a focus on oral cancers

SZ Farhad, A Karbalaeihasanesfahani… - Molecular Biology …, 2024 - Springer
Periodontitis is a severe gum infection that begins as gingivitis and can lead to gum
recession, bone loss, and tooth loss if left untreated. It is primarily caused by bacterial …

Matrix metalloproteinases regulate extracellular levels of SDF-1/CXCL12, IL-6 and VEGF in hydrogen peroxide-stimulated human periodontal ligament fibroblasts

F Cavalla, C Osorio, R Paredes, MA Valenzuela… - Cytokine, 2015 - Elsevier
Periodontitis is a highly prevalent infectious disease characterized by the progressive
inflammatory destruction of tooth-supporting structures, leading to tooth loss. The underling …

The influence of glycated hemoglobin on the cross susceptibility between type 1 diabetes mellitus and periodontal disease

DF Lappin, D Robertson, P Hodge… - Journal of …, 2015 - Wiley Online Library
Background: Periodontal disease is a major complication of type 1 diabetes mellitus (T1DM).
The aim of the present study is to investigate the relationship between glycated hemoglobin …