It is an urgent need that defect repair can develop from simple device fixation to living tissue
reconstruction, from short life function replacement to permanent regeneration repair. At …

Fabrication of functional scaffolds for tissue engineering and regenerative medicine
applications requires material systems with precise control over cellular performance. 3D …

Engineering a proper immune response following biomaterial implantation is essential to
bone tissue regeneration. Herein, a biomimetically hierarchical scaffold composed of …

Ideal bone scaffolds require good biocompatibility and moderate mechanical properties, so
as to promote the proliferation and differentiation of osteoblast cells, and achieve the good …

There are more than 2 million bone grafting procedures performed annually in the US alone.
Despite significant efforts, the repair of large segmental bone defects is a substantial clinical …

In severe tissue destruction, not only large number of cells are destroyed, but also the
extracellular matrix (ECM). The ECM is a three-dimensional (3D) network that provides …

Because of the good heat stability and similar mechanical properties to natural bone,
polyetheretherketone (PEEK) was widely used in preparation of prosthesis. While the …

Three-dimensional (3D) printing techniques for scaffold fabrication have shown promising
advancements in recent years owing to the ability of the latest high-performance printers to …

It is still a big challenge in orthopedics to treat infected bone defects properly using medical
metals. The use of three-dimensional (3D) scaffold materials that simultaneously mimic the …

Ti6Al4V is extensively utilized as orthopedic implants owing to its outstanding
biocompatibility and mechanical qualities. However, because Ti6Al4V has a high strength, it …