The secretome is defined as the set of molecules and biological factors that are secreted by
cells into the extracellular space. In the past decade, secretome-based therapies have …

The use of multipotent mesenchymal stem cells (MSCs) has been reported as promising for
the treatment of numerous degenerative disorders including the eye. In retinal degenerative …

Retinal ischemia is a major cause of vision loss and impairment and a common underlying
mechanism associated with diseases such as glaucoma, diabetic retinopathy, and central …

Mesenchymal stem cell (MSCs)-derived extracellular vesicles (EVs) are emerging
therapeutic tools. Hypoxic pre-conditioning (HPC) of MSCs altered the production of …

Purpose: To determine whether priming of bone marrow mesenchymal stem cells (MSCs) by
signals from injured retina, particularly tumor necrosis factor α (TNFα), increase their …

Research has shown that the therapeutic effect of mesenchymal stem cells (MSCs) is
partially due to its secreted factors as opposed to the implantation of the cells into the treated …

In recent years, studies have shown that the secretome of bone marrow mesenchymal
stromal cells (BMSCs) contains many growth factors, cytokines, and antioxidants, which may …

Mesenchymal stem cells are multipotent stem cells isolated from various tissue sources,
including but not limited to bone marrow, adipose, umbilical cord, and Wharton Jelly …

Purpose Ischemia-associated retinal degeneration is one of the leading causes of vision
loss, and to date, there are no effective treatment options. We hypothesized that delayed …

Introduction: Ocular and periocular traumatisms may result in loss of vision. Our previous
work showed that therapeutic hypothermia prevents retinal damage caused by traumatic …