Synthetic Applications of Amino Acid Derived Aldehydes in Asymmetric Hydroxylation Reactions Using Nitrosobenzene

VK Jain, S Dhillon, M Kinger - SynOpen, 2025 - thieme-connect.com
This review highlights the proline-catalyzed asymmetric α-hydroxylation of aldehydes
derived from amino acids. This reaction provides a robust method for introducing a hydroxyl …

Diastereoselectivity control in MAC methodology for the preparation of α-hydroxy-β-amino acid derivatives

X He - 2022 - theses.hal.science
The MAC methodology consists of using a protected hydroxymalononitrile derivative as an
umpolung reagent to allow the insertion of a carbonyl function between an electrophile and …