Hydrogels are crosslinked hydrophilic polymer structures that can imbibe large amounts of
water or biological fluids. Hydrogels are one of the upcoming classes of polymer-based …

The vagina, in addition to being a genital organ with functions related to conception, serves
as a potential route for drug administration. Mainly used for local action in the cervico …

This study described the thermosensitive formulations composed of poloxamer mixtures for
use as drug delivery platform via mucosal route. It also characterized the poloxamer …

Conventional materials technology has yielded clear improvements in regenerative
medicine. Ideally, however, a replacement material should mimic the living tissue …

Mucoadhesive nanoparticles (NPs) could be an exciting prospect for trans-nasal insulin
delivery as they have higher surface area to cover highly vascularised nasal absorptive area …

Vaginal HIV microbicides are topical, self administered products designed to prevent or
significantly reduce transmission of HIV infection in women. The earliest microbicide …

Nonirritant bioadhesive drug release systems based on starch–acrylic acid graft copolymers
prepared by radiation of starch and acrylic acid mixtures with 60Co were developed for …

The aim of our study was to prepare clomiphene citrate gel formulations that possess
appropriate mechanical properties, stay on the vaginal mucosa for a long period of time, and …

Mucoadhesion had been a topic of interest in the design of drug delivery system to prolong
the residence time of the dosage form with the under lying absorption surface to improve …

The aim of this study was to design and evaluate of mucoadhesive gel formulations for the
vaginal application of clomiphene citrate (CLM) for local treatment of human papilloma virus …