A review of effects of atorvastatin in cancer therapy

Z Shaghaghi, M Alvandi, S Farzipour, MR Dehbanpour… - Medical oncology, 2022 - Springer
Cancer is one of the most challenging diseases to manage. A sizeable number of
researches are done each year to find better diagnostic and therapeutic strategies. At the …

Alleviation of cisplatin‐induced hepatotoxicity by gliclazide: Involvement of oxidative stress and caspase‐3 activity

F Taghizadeh, SJ Hosseinimehr… - Pharmacology …, 2021 - Wiley Online Library
Aims Cisplatin (CP), as an effective alkylating agent, is widely used in cancer treatment,
while hepatotoxicity is one of its side effects. Gliclazide (GLZ), as an oral hypoglycemic drug …

Predicting acute radiation dermatitis in breast cancer: a prospective cohort study

Y Xie, T Hu, R Chen, H Chang, Q Wang, J Cheng - BMC cancer, 2023 - Springer
Background Acute radiation dermatitis (ARD) is one of the most common acute adverse
reactions in breast cancer patients during and immediately after radiotherapy. As ARD …

Potential utility of peptides against damage induced by ionizing radiation

Z Shaghaghi, M Alvandi, S Nosrati, SK Hadei - Future Oncology, 2021 - Taylor & Francis
Radioprotection is the process whereby biological systems are aided against undesirable
radiation hazards. Primitive radioprotectors suffered from either having crucial side effects or …

External validation of a predictive model for acute skin radiation toxicity in the REQUITE breast cohort

T Rattay, P Seibold, ME Aguado-Barrera… - Frontiers in …, 2020 - frontiersin.org
Background: Acute skin toxicity is a common and usually transient side-effect of breast
radiotherapy although, if sufficiently severe, it can affect breast cosmesis, aftercare costs and …

Gliclazide in Binary and Ternary Systems Improves Physicochemical Properties, Bioactivity, and Antioxidant Activity

M Ibrahim, S Munir, S Ahmed… - Oxidative Medicine …, 2022 - Wiley Online Library
The poor solubility of the antidiabetic drug gliclazide (Glc) is due to its hydrophobic nature.
This research is aimed at improving Glc's solubility and drug release profile, as well as at …

[PDF][PDF] Radiation and hypoxia studies: effects of high-energy atmospheric particles on biological organisms and possibilities of their rehabilitation

OM Klyuchko, GV Lizunov, PV Beloshitsky - Biotechnologia Acta, 2023 - researchgate.net
Methods. Analysis of results of satellite and rocket observations of the Earth atmosphere
gases exploring at different altitudes asl The investigations were done in mountain …

High throughput screen of small molecules as potential countermeasures to galactic cosmic radiation induced cellular dysfunction

M Weiss, B Nikisher, H Haran, K Tefft, J Adams… - Life Sciences in Space …, 2022 - Elsevier
Abstract Space travel increases galactic cosmic ray exposure to flight crews and this is
significantly elevated once travel moves beyond low Earth orbit. This includes combinations …

Radioprotective effect of zinc nanoparticles on ionizing radiation-induced nephrotoxicity in mice

I Saadat, M Shakibaie, A Jomehzadeh, A Salimi… - Pharmacology, 2023 - karger.com
Introduction: Ionizing radiation (IR) causes oxidative stress in kidneys and subsequently
disrupts renal function. The use of green synthesized zinc nanoparticles (Zn NPs) with …

Comparative solubilization of Gliclazide in solutions of two anionic micelles with asymmetrical hydrophobic chain length: An experimental and theoretical analysis

S Anjali, R Vigneshwari, B Balasubramaniyan… - Journal of Molecular …, 2024 - Elsevier
Gliclazide (GCL) is used widely for reducing hyperglycemia in diabetic patients. It has poor
solubility which leads to low oral bioavailability because of significant first-pass metabolism …