Physical exercise may improve cognitive function by modulating molecular and cellular
mechanisms within the brain. We propose that the facilitation of long-term synaptic …

Introduction: Myokines, known to mediate metabolism, inflammation, and other
pathophysiological conditions, have been widely investigated, including myokines induced …

Previous studies have shown the role of apelin and its receptors in the regulation of food
intake. In the present study, we investigate the mediating role of melanocortin, corticotropin …

Background: Multiple factors, including neurobiological, hormonal, psychological, and
social/cultural norms, influence the manner in which individuals experience pain. Adipose …

The initiation and progression of neurodegenerative diseases (NDs), distinguished by
compromised nervous system integrity, profoundly disrupt the quality of life of patients …

Apelin is an endogenous ligand of G protein-coupled receptor APJ. Apelin/APJ system is
widely expressed in abundant tissues, especially bone, joint and muscle tissue. This review …

The purpose of this study was to determine the effects of different concentrations of
ligustrazine, an extract from Chinese herb, on ketamine requirement for hypnosis and …

Physical effort is one of the key aspects of keeping horses in good condition. The condition
of the animal is reflected by multiple blood parameters. The newly discovered cytokine …

Aim: The present study aimed to investigate the effect of twelve weeks of combined training
and subsequent eight weeks of detraining on apelin levels in type 2 diabetic women …

Background and Aim: Type 1 diabetes has been considered among of the metabolic
diseases in various societies. Some research indicated that exercise and supplementation …