CONTEXT: Brain injury is the most common long-term complication of congenital heart
disease requiring surgery during infancy. It is clear that the youngest patients undergoing …

The development of systems that allow cardiopulmonary bypass have been responsible for
the growth of our specialty. In recent years continuing reduction in the mortality associated …

OBJECTIVES: Our goal was to determine which of the two major methods of vital organ
support used in infant cardiac surgery, total circulatory arrest and low-flow cardiopulmonary …

The management of congenital heart disease has changed dramatically over the last 15
years and continues to evolve at a rapid pace. More than ever before contemporary practice …

BACKGROUND: New intraparenchymal brain injury on magnetic resonance imaging is
observed in 36% to 73% of neonates after cardiac surgery with cardiopulmonary bypass …

Background—Near-infrared spectroscopy monitoring of cerebral oxygen saturation (rSo2)
has become routine in many centers, but no studies have reported the relationship of …

Objectives: In a randomized, single-center trial, we compared perioperative outcomes in
infants undergoing cardiac operations after use of the alpha-stat versus pH-stat strategy …

OBJECTIVES: Neurologic deficits are common after the Norwood procedure for hypoplastic
left heart syndrome. Because of the association of deep hypothermic circulatory arrest with …

OBJECTIVES: Stage 1 palliation of hypoplastic left heart syndrome requires the interruption
of whole-body perfusion. Delayed reflow in the cerebral circulation secondary to prolonged …

Objectives: In a randomized single-center trial, we compared developmental and neurologic
outcomes at 1 and 2 to 4 years of age in children who underwent reparative cardiac …