Purpose To review the evidence supporting diabetic retinal neurodegeneration (DRN) as a
form of diabetic retinopathy. Method Review of literature. Results DRN is recognized to be a …

Following the fast pace of the growing field of stem cell research, retinal cell replacement is
finally emerging as a feasible mean to be explored for clinical application. Although …

Unlike mammals, some nonmammalian species recruit Müller glia for retinal regeneration
after injury. Identifying the underlying mechanisms may help to foresee regenerative …

Retinal degenerative diseases, including age-related macular degeneration (AMD) and
retinitis pigmentosa, lack effective therapies. Conventional monotherapeutic approaches fail …

Diabetic retinopathy (DR) is a common microvascular complication of diabetes necessitating
early intervention to impede progression, despite current clinical treatments focusing on …

Müller glia are specialized retinal cells with stem cell properties in fish and frogs but not in
mammals. Current efforts to develop gene therapies to activate mammalian Müller glia for …

Background Contrasting with zebrafish, retinal regeneration from Müller cells (MCs) is
largely limited in mammals, where they undergo reactive gliosis that consist of a …

The possible applications for human retinal organoids (HROs) derived from human induced
pluripotent stem cells (hiPSC) rely on the robustness and transferability of the methodology …

Purpose: Retinal explant cultures provide simplified systems where the functions of the
retina and the effects of ocular therapies can be studied in an isolated environment. The …

Blast-mediated traumatic brain injuries (bTBI) cause long-lasting physical, cognitive, and
psychological disorders, including persistent visual impairment. No known therapies are …