Astrocytic MicroRNAs and transcription factors in Alzheimer's disease and therapeutic interventions

A Nassar, T Kodi, S Satarker, P Chowdari Gurram… - Cells, 2022 - mdpi.com
Astrocytes are important for maintaining cholesterol metabolism, glutamate uptake, and
neurotransmission. Indeed, inflammatory processes and neurodegeneration contribute to …

Exploring the underlying mechanisms of obesity and diabetes and the potential of Traditional Chinese Medicine: an overview of the literature

Y Chen, T Liu, FKF Teia, M Xie - Frontiers in Endocrinology, 2023 - frontiersin.org
Obesity and diabetes are closely related metabolic disorders that have become major public
health concerns worldwide. Over the past few decades, numerous studies have explored the …

The role of microRNAs in the molecular link between circadian rhythm and autism spectrum disorder

JY Kim, W Kim, KH Lee - Animal Cells and Systems, 2023 - Taylor & Francis
Circadian rhythm regulates physiological cycles of awareness and sleepiness. Melatonin
production is primarily regulated by circadian regulation of gene expression and is involved …

Effects of brain microRNAs in cognitive trajectory and Alzheimer's disease

SM Vattathil, SSM Tan, PJ Kim, DA Bennett… - Acta …, 2024 - Springer
Abstract microRNAs (miRNAs) have a broad influence on gene expression; however, we
have limited insights into their contribution to rate of cognitive decline over time or …

The effects of resistance training and spirulina on the performance of the antioxidant system with emphasis on mir125b, mir146a and cognitive function in stanazolol …

MRH Agahi, Z Mosallanejad, OR Salehi - Chemico-Biological Interactions, 2022 - Elsevier
Abuse of anabolic-androgenic steroids (AAS) is associated with neurological and cognitive
problems in athletes. The Purpose of this study was to investigate the simultaneous effect of …

Adult rats sired by obese fathers present learning deficits associated with epigenetic and neurochemical alterations linked to impaired brain glutamatergic signaling

CE Mezo‐González, JA García‐Santillán… - Acta …, 2024 - Wiley Online Library
Aim Offspring of obese mothers are at high risk of developing metabolic syndrome and
cognitive disabilities. Impaired metabolism has also been reported in the offspring of obese …

Paradoxical attenuation of neuroinflammatory response upon LPS challenge in miR-146b deficient mice

K Chithanathan, M Jürgenson, M Guha, L Yan… - Frontiers in …, 2022 - frontiersin.org
The miR-146 family consists of two microRNAs (miRNAs), miR-146a and miR-146b (miR-
146a/b), both of which are known to suppress immune responses in a variety of conditions …

MicroRNA‐146a‐5p protects retinal ganglion cells through reducing neuroinflammation in experimental glaucoma

H Zhou, RK Yang, Q Li, Z Li, YC Wang, SY Li, Y Miao… - Glia, 2024 - Wiley Online Library
Neuroinflammation plays important roles in retinal ganglion cell (RGC) degeneration in
glaucoma. MicroRNA‐146 (miR‐146) has been shown to regulate inflammatory response in …

Elocalcitol mitigates high-fat diet-induced microglial senescence via miR-146a modulation

K Chithanathan, M Jürgenson, K Ducena, A Remm… - Immunity & …, 2024 - Springer
Background MicroRNAs (miRNAs) play crucial roles in regulating inflammation and cellular
senescence. Among them, miR-146a has emerged as a key modulator of inflammation, but …