Cefazolin inoculum effect and methicillin-susceptible Staphylococcus aureus osteoarticular infections in children

JC McNeil, LM Sommer, M Boyle… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Select methicillin-susceptible Staphylococcus aureus (MSSA) strains may produce β-
lactamases with affinity for first-generation cephalosporins (1GCs). In the setting of a high …

Shedding light on amoxicillin, amoxicillin-clavulanate, and cephalexin dosing in children from a pharmacist's perspective

D Yu, LL Bio - Journal of the Pediatric Infectious Diseases …, 2022 - academic.oup.com
Selection of an antibiotic and dosing regimen requires consideration of multiple factors
including microbiological data, site of infection, pharmacokinetics, and how it relates to the …

Cefadroxil and cephalexin pharmacokinetics and pharmacodynamics in children with musculoskeletal infections

AS Haynes, Z Wei, P Anderson… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Cephalexin, a first-generation cephalosporin, is the first-line oral therapy for children with
musculoskeletal infections due to methicillin-susceptible Staphylococcus aureus (MSSA) …

Cefadroxil comparable to cephalexin: minimum inhibitory concentrations among methicillin-susceptible Staphylococcus aureus isolates from pediatric musculoskeletal …

AS Haynes, A Prinzi, LJ Silveira, SK Parker… - Microbiology …, 2022 - Am Soc Microbiol
Cephalexin and cefadroxil are oral first-generation cephalosporins used to treat methicillin-
susceptible Staphylococcus aureus (MSSA) infections. Despite its shorter half-life …

Efficacy and tolerability of high-dose cefalexin 45 mg/kg/dose (maximum 1.5 g) three times daily in children with bone and joint infections

S Hikmat, A Boast, N Curtis… - Journal of Antimicrobial …, 2024 - academic.oup.com
Background Cefalexin, a first-generation cephalosporin, is commonly used as oral
continuation therapy for paediatric bone and joint infections (BJIs). The standard four times …

What's New in Pediatric Orthopaedics

LM Andras, JS Sanders, RY Goldstein, JB Samora - JBJS, 2023 - journals.lww.com
Trauma Supracondylar Humeral Fractures In a series of nearly 700 patients, the use of a
mini-open approach for the placement of a medial pin resulted in only a 0.43% rate of …