Cancer is a condition that has plagued humanity for thousands of years, with the first
depictions dating back to ancient Egyptian times. However, not until recent decades have …

Monoclonal antibody-based targeted therapies have greatly improved treatment options for
patients by binding to the innate immune system. However, the long-term efficacy of such …

Antibody-protein conjugates have been useful tools for studying biological systems and also
played important roles in developing therapeutics and diagnostics. In particular, because of …

In the continuous exploration of the VHH chemistry, biochemistry and therapeutic future use,
we investigated two different production strategies of this small antibody‐like protein, using …

TrYbe® is an Fc-free therapeutic antibody format, capable of engaging up to three targets
simultaneously, with long in vivo half-life conferred by albumin binding. This format is shown …

Six months after the publication of the severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) sequence, a record number of vaccine candidates were listed, and quite a …

Development of cancers mostly involves more than one signal pathways, because of the
complicated nature of cancer cells. As such, the most effective treatment option is the one …

The emergence of bispecific antibodies has transformed cancer immunotherapy,
highlighting increased clinical efficacy, especially in hematological malignancies. These …