Pancreatic ductal adenocarcinoma (PDA), the most frequent type of pancreatic cancer,
remains one of the most challenging problems for the biomedical and clinical fields, with …

Hepatocytes, like other epithelia, are situated at the interface between the organism's
exterior and the underlying internal milieu and organize the vectorial exchange of …

The role of inflammation in carcinogenesis has been extensively investigated and well
documented. Many biochemical processes that are altered during chronic inflammation …

After years of in-depth research on immune checkpoints, therapeutic reversal of immune-
exhaustion with immune checkpoint inhibitors (ICPIs) has been shown to be effective in …

Galectins, a family of evolutionarily conserved glycan-binding proteins, play key roles in
diverse biological processes including tissue repair, adipogenesis, immune cell …

Galectin family members have been shown to exert multiple roles in the context of tumor
biology. Several recent findings support a similar multi-faceted role for galectin-9. Galectin-9 …

Abstract Galectin-1 (GAL1), a β-galactoside-binding protein abundantly expressed in the
tumor microenvironment, has emerged as a key mechanism of chemoresistance developed …

Changes in cell growth and metabolism are affected by the surrounding environmental
factors to adapt to the cell's most appropriate growth model. However, abnormal cell …

Hepatocellular carcinoma (HCC) is one of the most common cancers in Taiwan. Although
chemotherapy is the primary treatment for HCC patients, drug resistance often leads to …

Galectin‐1 (Gal1), a β‐galactoside‐binding protein abundantly expressed in tumor
microenvironments, is associated with the development of metastasis in hepatocellular …