Of linkers and autochaperones: an unambiguous nomenclature to identify common and uncommon themes for autotransporter secretion
I Drobnak, E Braselmann, JL Chaney… - Molecular …, 2015 - Wiley Online Library
Autotransporter (AT) proteins provide a diverse array of important virulence functions to G
ram‐negative bacterial pathogens, and have also been adapted for protein surface display …
ram‐negative bacterial pathogens, and have also been adapted for protein surface display …
Influence of Shigella flexneri 2a O antigen acetylation on its bacteriophage Sf6 receptor activity and bacterial interaction with human cells
Shigella flexneri is a major causative agent of bacillary dysentery in developing countries,
where serotype 2a2 is the prevalent strain. To date, approximately 30 serotypes have been …
where serotype 2a2 is the prevalent strain. To date, approximately 30 serotypes have been …
Charge-dependent secretion of an intrinsically disordered protein via the autotransporter pathway
W Kang'ethe, HD Bernstein - Proceedings of the National …, 2013 - National Acad Sciences
Autotransporters are a large class of virulence proteins produced by Gram-negative
bacteria. They contain an N-terminal extracellular (“passenger”) domain that folds into a β …
bacteria. They contain an N-terminal extracellular (“passenger”) domain that folds into a β …
DegP chaperone suppresses toxic inner membrane translocation intermediates
The periplasm of Gram-negative bacteria includes a variety of molecular chaperones that
shepherd the folding and targeting of secreted proteins. A central player of this quality …
shepherd the folding and targeting of secreted proteins. A central player of this quality …
Bacteriophage Sf6 host range mutant that infects Shigella flexneri serotype 2a2 strains
Shigella flexneri serotype 2a2 (II: 9; 10) is the most prevalent strain in causing bacillary
dysentery in developing countries. Chemical modifications such as glucosylation, O …
dysentery in developing countries. Chemical modifications such as glucosylation, O …
Construction of a plasmid that expresses an N-terminally 6xHis tagged protein spanning amino acids Gly139 to Pro552 of the passenger domain of the Escherichia …
R Leong, S Safaeian, J Zhang - Undergraduate Journal of …, 2024 - ojs.library.ubc.ca
Escherichia coli, a Gram-negative bacterium, exhibits resistance to multiple antibiotics,
emphasising the need for novel targets. Autotransporter (AT) proteins, such as Antigen 43 …
emphasising the need for novel targets. Autotransporter (AT) proteins, such as Antigen 43 …
Identification of Shigella flexneri IcsA Residues Affecting Interaction with N-WASP, and Evidence for IcsA-IcsA Co-Operative Interaction
The Shigella flexneri IcsA (VirG) protein is a polarly distributed outer membrane protein that
is a fundamental virulence factor which interacts with neural Wiskott-Aldrich syndrome …
is a fundamental virulence factor which interacts with neural Wiskott-Aldrich syndrome …
An alternative outer membrane secretion mechanism for an autotransporter protein lacking a C‐terminal stable core
RN Besingi, JL Chaney, PL Clark - Molecular microbiology, 2013 - Wiley Online Library
Autotransporter (AT) proteins are a broad class of virulence factors from Gram‐negative
pathogens. AT outer membrane (OM) secretion appears simple in many regards, yet the …
pathogens. AT outer membrane (OM) secretion appears simple in many regards, yet the …
LPS Unmasking of Shigella flexneri Reveals Preferential Localisation of Tagged Outer Membrane Protease IcsP to Septa and New Poles
The Shigella flexneri outer membrane (OM) protease IcsP (SopA) is a member of the
enterobacterial Omptin family of proteases which cleaves the polarly localised OM protein …
enterobacterial Omptin family of proteases which cleaves the polarly localised OM protein …
A small conserved motif supports polarity augmentation of Shigella flexneri IcsA
The rod-shaped enteric intracellular pathogen Shigella flexneri and other Shigella species
are the causative agents of bacillary dysentery. S. flexneri are able to spread within the …
are the causative agents of bacillary dysentery. S. flexneri are able to spread within the …