The growing worldwide burden of insulin resistance (IR) emphasizes the importance of early
identification for improved management. Obesity, particularly visceral obesity, has been a …

Dendritic cells (DCs) function is intimately linked to microenvironment and metabolism. Type
I interferons (IFNs) condition dendritic cells to respond to weak self-signals, leading to …

Aim Previous studies have shown that silent information regulator 1 (SIRT1) expression is
elevated in rheumatoid arthritis (RA) patients. However, whether gene polymorphisms in …

The global prevalence for diabetes mellitus nearly doubled from 4.7% in 1980 to 8.5% in
2014. Sirtuin 1 (SIRT1) is an NAD+-dependent deacetylase that is expressed in a variety of …

Acute lymphoblastic leukemia (ALL) is the most frequently diagnosed cancer in children and
single‐nucleotide polymorphisms (SNPs) in certain genes influence risk of ALL. Although …

Background Psoriasis vulgaris is a chronic, relapsing, inflammatory disorder marked by an
intensified immune response. The role of immunogenetics in psoriasis is still poorly …

Background Premature myocardial infarction (PMI) is one of the most pressing global issues
in modern cardiology. Recently, the incidence of PMI has gradually increased. Researches …

Background: Grape seed is a natural herb with many suggested pharmacological effects
related to many biologically active compounds in its extract and fractions. Grape seed …

За результатами дослідження було запропоноване нове вирішення нагальної
проблеми сучасної кардіології-удосконалення прогнозування та діагностики хронічної …

Aim: The aim of our study is to analyze the SIRT1 gene rs2273773, rs7895833 and
rs7069102 polymorphisms and the association of SIRT1 gene and interacting genes with …